Pair Name	Sulforaphene, Photodynamic therapy
Partner Name	Sulforaphene
Disease Info	[ICD-11: 2D10.Z]	Thyroid cancer		Investigative
Biological Phenomena	Induction-->ROS generation
Gene Regulation	Down-regulation	Phosphorylation	BRAF	hsa673
	Down-regulation	Expression	KRAS	hsa3845
	Down-regulation	Phosphorylation	MAP2K2	hsa5605
	Down-regulation	Phosphorylation	MAP2K7	hsa5609
	Down-regulation	Phosphorylation	MAPK1	hsa5594
	Down-regulation	Phosphorylation	MAPK14	hsa1432
	Down-regulation	Phosphorylation	MAPK3	hsa5595
In Vitro Model	FRO	Thyroid gland anaplastic carcinoma	Homo sapiens (Human)	CVCL_6287
Result	Our work designates sulforaphene as a unique natural enhancer of efficacy with PDT against anaplastic thyroid cancer.

Pair Name	Sulforaphene, Photodynamic therapy
Partner Name	Sulforaphene
Disease Info	[ICD-11: 2C77]	Cervical cancer		Investigative
Biological Phenomena	Induction-->Apoptosis
Gene Regulation	Up-regulation	Expression	BAX	hsa581
	Down-regulation	Expression	BCL2	hsa596
	Up-regulation	Expression	CASP12	hsa100506742
	Up-regulation	Expression	CASP3	hsa836
	Up-regulation	Expression	CASP8	hsa841
	Up-regulation	Expression	CASP9	hsa842
	Up-regulation	Expression	CYCS	hsa54205
	Up-regulation	Expression	DDIT3	hsa1649
	Down-regulation	Expression	EGFR	hsa1956
In Vitro Model	HeLa	Human papillomavirus-related cervical adenocarcinoma	Homo sapiens (Human)	CVCL_0030
Result	This study could be useful in the improvement of therapies for human cervical and other types of cancers.