InterPAD - DETAILS

indomethacin, 53-86-1, indometacin, Indocin, Indomethacine, Indometacine, Indocid, Reumacide, Indomethazine, Metindol, Artrinovo, Confortid, Idomethine, Indomecol, Indomethacinum, Metartril, Methazine, Artrivia, Dolovin, Imbrilon, Indacin, Indomed, Indomee, Indoptol, Infrocin, Metacen, Sadoreum, Amuno, Inacid, Tannex, Indo-rectolmin, Inteban sp, Artracin, Durametacin, Indoptic, Inflazon, Mikametan, Lausit, Mezolin, Mobilan, Indo-tablinen, Indo-Lemmon, Indometacinum, Indometacyna, Indometicina, Indocin Sr, Indometacina, Aconip, 2-(1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid, Indmethacine, Dolcidium, Elmetacin, Indomethine, Indorektal, Tivorbex, Catlep, Indoxen, Vonum, 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, Indo-phlogont, Chibro-amuno, Bonidon Gel, Dolcidium PL, Rheumacin LA, Osmosin, 1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid, CCRIS 3502, HSDB 3101, Indometacine [INN-French], Indometacinum [INN-Latin], Indometacina [INN-Spanish], FLAM, Inteban, 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid, NCI-C56144, UNII-XXE1CET956, 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid, 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid, EINECS 200-186-5, XXE1CET956, MFCD00057095, Indometacin [INN], NSC-757061, 1-(p-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acid, BRN 0497341, USAN, Indomethacin (Indocid, Indocin), CHEBI:49662, CHEMBL6, NSC-77541, IMN, Indole-3-acetic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-, Indomethacin [USAN:USP], alpha-(1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolyl)acetic acid, 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1h-indol-3-yl}acetic acid, N-p-Chlorbenzoyl-5-methoxy-2-methylindole-3-acetic acid, MLS000069402, DTXSID9020740, (1-p-Chlorobenzoyl-5-methoxy-2-methylindol-3-yl)acetic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indolylacetic acid, 1-(p-Chlorobenzoyl)-2-methoxy-3-methyl-1H-indole-3-acetic Acid, Indomet 140, EC 200-186-5, [1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid, 5-22-05-00239 (Beilstein Handbook Reference), {1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid, NSC 757061, CAS-53-86-1, 1-p-Cloro-benzoil-5-metoxi-2-metilindol-3-acido acetico, NCGC00015562-18, Indomethancin, 1-(4-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid, Arthrexin, Bonidin, Bonidon, Indameth, Indomod, Miametan, SMR000058195, Indomo, Flexin continus, Hicin, Kwas 1-(p-chlorobenzoilo)-2-metylo-5-metoksy-3-indolilooctowy, Chrono-indicid, Chrono-indocid, Indometacyna [Polish], Indometicina [Spanish], 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid, Indo-Spray, Indomethacin (USAN:USP), Indolar SR, Indometacine (INN-French), Indometacinum (INN-Latin), Indometacina (INN-Spanish), INDOMETACIN (MART.), INDOMETACIN [MART.], DTXCID50740, INDOMETHACIN (USP-RS), INDOMETHACIN [USP-RS], 1-(p-chlorobenzoyl)-2-methyl-5-methoxy-3-indoleacetic acid, INDOMETACIN (EP MONOGRAPH), INDOMETACIN [EP MONOGRAPH], INDOMETHACIN (USP MONOGRAPH), INDOMETHACIN [USP MONOGRAPH], 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-indol-3-yl]acetic acid, (1-(4-CHLOROBENZOYL)-5-METHOXY-2-METHYL-1H-INDOL-3-YL)ACETIC ACID, 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl}acetic acid, Indocin-SR, Indochron E-R, Indocin (TN), ACEMETACIN IMPURITY B (EP IMPURITY), ACEMETACIN IMPURITY B [EP IMPURITY], Aconip (TN), Indomethacin (USP), NSC77541, Indocid (pharmaceutical), SR-01000000014, Indomethacin & MAP-30, Indocollyre, Indonol, Innamit, 1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-Indole-3-acetic acid, IndomethacinER, Indomethacin ER, 2-{1-((4-chlorophenyl)carbonyl)-5-methoxy-2-methylindol-3-yl}acetic acid, 4kyk, (1-((4-chlorophenyl)carbonyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid, Indomethacin,(S), Prestwick_597, INDREN, Indometacinum (Latin), Opera_ID_56, Spectrum_000919, Tocris-1708, 1z9h, 1-(p-Chlorbenzoyl)-5-methoxy-2-methylindol-3-essigsaeure [German], 1-p-Cloro-benzoil-5-metoxi-2-metilindol-3-acido acetico [Spanish], Prestwick0_000272, Prestwick1_000272, Prestwick2_000272, Prestwick3_000272, Spectrum2_000970, Spectrum3_000468, Spectrum4_000018, Spectrum5_000868, INDOMETACIN [JAN], INDOMETHACIN [MI], Lopac-I-7378, Kwas 1-(p-chlorobenzoilo)-2-metylo-5-metoksy-3-indolilooctowy [Polish], CHRONO-INDOCID 75, MolMap_000032, UPCMLD-DP023, I 7378, Indometacin (JP17/INN), INDOMETHACIN [HSDB], INDOMETHACIN [USAN], SCHEMBL9300, INDOMETHACIN [VANDF], Indomethacin Extended-release, Lopac0_000692, Oprea1_686105, BSPBio_000144, BSPBio_001149, BSPBio_002176, INDOMETACIN [WHO-DD], INDOMETACIN [WHO-IP], Indomethacine impurity mixture, KBioGR_000395, KBioGR_000489, KBioSS_000489, KBioSS_001399, MLS001074194, MLS006011845, BIDD:GT0132, DivK1c_000271, SPECTRUM1500350, SPBio_000979, SPBio_002363, BPBio1_000160, GTPL1909, Indomethacin, >=99% (TLC), UPCMLD-DP023:001, BDBM17638, CGIGDMFJXJATDK-UHFFFAOYSA-, HMS500N13, KBio1_000271, KBio2_000489, KBio2_001399, KBio2_003057, KBio2_003967, KBio2_005625, KBio2_006535, KBio3_000897, KBio3_000898, KBio3_001396, 1-(p-Chlorbenzoyl)-5-methoxy-2-methylindol-3-essigsaeure, C01EB03, M01AB01, M02AA23, S01BC01, Indomethacin - CAS 53-86-1, NINDS_000271, Bio2_000405, Bio2_000885, HMS1362I11, HMS1568H06, HMS1792I11, HMS1920F21, HMS1990I11, HMS2089N19, HMS2091N09, HMS2095H06, HMS2231J10, HMS3262K05, HMS3268A14, HMS3374F07, HMS3403I11, HMS3414N13, HMS3430L03, HMS3649K17, HMS3655O04, HMS3678N11, HMS3712H06, HMS3747K21, HMS3884E08, INDOMETHACIN [ORANGE BOOK], Indomethacin-d4(chlorobenzoyl-d4), Pharmakon1600-01500350, BCP18951, Indomethacin, >=99.0% (TLC), Tox21_113109, Tox21_201791, Tox21_300266, Tox21_500692, AC-532, CCG-40186, HB4422, INDOMETACINUM [WHO-IP LATIN], NSC757061, s1723, STL257874, AKOS000592893, Tox21_113109_1, AT13679, DB00328, Indometacin 1.0 mg/ml in Acetonitrile, KS-5255, LP00692, SDCCGSBI-0050670.P005, IDI1_000271, IDI1_002160, NCGC00015562-01, NCGC00015562-02, NCGC00015562-03, NCGC00015562-04, NCGC00015562-05, NCGC00015562-06, NCGC00015562-07, NCGC00015562-08, NCGC00015562-09, NCGC00015562-10, NCGC00015562-11, NCGC00015562-12, NCGC00015562-13, NCGC00015562-14, NCGC00015562-15, NCGC00015562-16, NCGC00015562-17, NCGC00015562-19, NCGC00015562-20, NCGC00015562-21, NCGC00015562-22, NCGC00015562-24, NCGC00015562-25, NCGC00015562-40, NCGC00024135-02, NCGC00024135-04, NCGC00024135-05, NCGC00024135-06, NCGC00024135-07, NCGC00024135-08, NCGC00024135-09, NCGC00024135-10, NCGC00024135-11, NCGC00024135-12, NCGC00024135-13, NCGC00024135-14, NCGC00024135-15, NCGC00254075-01, NCGC00259340-01, NCGC00261377-01, BI166166, BP-30207, HY-14397, NCI60_041708, O-Desmethyl-des-4-chlorobenzoylacemetacin, SBI-0050670.P004, DB-052413, AB00052022, EU-0100692, FT-0603227, I0655, NS00000217, SW196768-5, EN300-16807, Indomethacin, meets USP testing specifications, BIM-0050670.0001, C01926, D00141, S00108, AB00052022-20, AB00052022-21, AB00052022_23, AB00052022_24, L000959, Q409231, Indomethacin, Antibiotic for Culture Media Use Only, Q-201239, SR-01000000014-2, SR-01000000014-4, SR-01000000014-6, 1-(4-Chlorobenzoyl)-5-methoxy-2-met hyl-1H-indole, BRD-K57222227-001-06-1, BRD-K57222227-001-18-6, BRD-K57222227-001-27-7, SR-01000000014-10, SR-01000000014-16, Z56784896, 1-p-chlorobenzoyl-2-methyl-5-methoxyindol-3-acetic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid, 1-(p-Chlorobenzoyl)-5-methoxy-2-methylindol-3-acetic acid, 1-(p-chlorobenzyl)-5-methoxy-2-methylindole-3-acetic acid, 1-(4-chloro-benzoyl)-5-methoxy-2-methyl-3-indolyl-acetic acid, 1-(4-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acid, 1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indole-acetic acid, 1-(p-chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indol acetic acid, Indomethacin, European Pharmacopoeia (EP) Reference Standard, N-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1-H-indole-3-acetic acid, Indomethacin, United States Pharmacopeia (USP) Reference Standard, N-P-CHLOROBENZOYL-5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID, .alpha.-(1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolyl)acetic acid, [1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid #, 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid & MAP-30, 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl- (9CI), 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2 methylindol-3-yl}acetic acid, 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2methylindol-3-yl}acetic acid, Indole-3-acetic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl- (8CI), Indomethacin, Pharmaceutical Secondary Standard; Certified Reference Material, InChI=1/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)

Name	Indomethacin
PubChem CID	3715
Molecular Weight	357.8g/mol
Synonyms	indomethacin, 53-86-1, indometacin, Indocin, Indomethacine, Indometacine, Indocid, Reumacide, Indomethazine, Metindol, Artrinovo, Confortid, Idomethine, Indomecol, Indomethacinum, Metartril, Methazine, Artrivia, Dolovin, Imbrilon, Indacin, Indomed, Indomee, Indoptol, Infrocin, Metacen, Sadoreum, Amuno, Inacid, Tannex, Indo-rectolmin, Inteban sp, Artracin, Durametacin, Indoptic, Inflazon, Mikametan, Lausit, Mezolin, Mobilan, Indo-tablinen, Indo-Lemmon, Indometacinum, Indometacyna, Indometicina, Indocin Sr, Indometacina, Aconip, 2-(1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid, Indmethacine, Dolcidium, Elmetacin, Indomethine, Indorektal, Tivorbex, Catlep, Indoxen, Vonum, 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, Indo-phlogont, Chibro-amuno, Bonidon Gel, Dolcidium PL, Rheumacin LA, Osmosin, 1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid, CCRIS 3502, HSDB 3101, Indometacine [INN-French], Indometacinum [INN-Latin], Indometacina [INN-Spanish], FLAM, Inteban, 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid, NCI-C56144, UNII-XXE1CET956, 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid, 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid, EINECS 200-186-5, XXE1CET956, MFCD00057095, Indometacin [INN], NSC-757061, 1-(p-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acid, BRN 0497341, USAN, Indomethacin (Indocid, Indocin), CHEBI:49662, CHEMBL6, NSC-77541, IMN, Indole-3-acetic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-, Indomethacin [USAN:USP], alpha-(1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolyl)acetic acid, 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1h-indol-3-yl}acetic acid, N-p-Chlorbenzoyl-5-methoxy-2-methylindole-3-acetic acid, MLS000069402, DTXSID9020740, (1-p-Chlorobenzoyl-5-methoxy-2-methylindol-3-yl)acetic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indolylacetic acid, 1-(p-Chlorobenzoyl)-2-methoxy-3-methyl-1H-indole-3-acetic Acid, Indomet 140, EC 200-186-5, [1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid, 5-22-05-00239 (Beilstein Handbook Reference), {1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid, NSC 757061, CAS-53-86-1, 1-p-Cloro-benzoil-5-metoxi-2-metilindol-3-acido acetico, NCGC00015562-18, Indomethancin, 1-(4-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid, Arthrexin, Bonidin, Bonidon, Indameth, Indomod, Miametan, SMR000058195, Indomo, Flexin continus, Hicin, Kwas 1-(p-chlorobenzoilo)-2-metylo-5-metoksy-3-indolilooctowy, Chrono-indicid, Chrono-indocid, Indometacyna [Polish], Indometicina [Spanish], 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid, Indo-Spray, Indomethacin (USAN:USP), Indolar SR, Indometacine (INN-French), Indometacinum (INN-Latin), Indometacina (INN-Spanish), INDOMETACIN (MART.), INDOMETACIN [MART.], DTXCID50740, INDOMETHACIN (USP-RS), INDOMETHACIN [USP-RS], 1-(p-chlorobenzoyl)-2-methyl-5-methoxy-3-indoleacetic acid, INDOMETACIN (EP MONOGRAPH), INDOMETACIN [EP MONOGRAPH], INDOMETHACIN (USP MONOGRAPH), INDOMETHACIN [USP MONOGRAPH], 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-indol-3-yl]acetic acid, (1-(4-CHLOROBENZOYL)-5-METHOXY-2-METHYL-1H-INDOL-3-YL)ACETIC ACID, 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl}acetic acid, Indocin-SR, Indochron E-R, Indocin (TN), ACEMETACIN IMPURITY B (EP IMPURITY), ACEMETACIN IMPURITY B [EP IMPURITY], Aconip (TN), Indomethacin (USP), NSC77541, Indocid (pharmaceutical), SR-01000000014, Indomethacin & MAP-30, Indocollyre, Indonol, Innamit, 1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-Indole-3-acetic acid, IndomethacinER, Indomethacin ER, 2-{1-((4-chlorophenyl)carbonyl)-5-methoxy-2-methylindol-3-yl}acetic acid, 4kyk, (1-((4-chlorophenyl)carbonyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid, Indomethacin,(S), Prestwick_597, INDREN, Indometacinum (Latin), Opera_ID_56, Spectrum_000919, Tocris-1708, 1z9h, 1-(p-Chlorbenzoyl)-5-methoxy-2-methylindol-3-essigsaeure [German], 1-p-Cloro-benzoil-5-metoxi-2-metilindol-3-acido acetico [Spanish], Prestwick0_000272, Prestwick1_000272, Prestwick2_000272, Prestwick3_000272, Spectrum2_000970, Spectrum3_000468, Spectrum4_000018, Spectrum5_000868, INDOMETACIN [JAN], INDOMETHACIN [MI], Lopac-I-7378, Kwas 1-(p-chlorobenzoilo)-2-metylo-5-metoksy-3-indolilooctowy [Polish], CHRONO-INDOCID 75, MolMap_000032, UPCMLD-DP023, I 7378, Indometacin (JP17/INN), INDOMETHACIN [HSDB], INDOMETHACIN [USAN], SCHEMBL9300, INDOMETHACIN [VANDF], Indomethacin Extended-release, Lopac0_000692, Oprea1_686105, BSPBio_000144, BSPBio_001149, BSPBio_002176, INDOMETACIN [WHO-DD], INDOMETACIN [WHO-IP], Indomethacine impurity mixture, KBioGR_000395, KBioGR_000489, KBioSS_000489, KBioSS_001399, MLS001074194, MLS006011845, BIDD:GT0132, DivK1c_000271, SPECTRUM1500350, SPBio_000979, SPBio_002363, BPBio1_000160, GTPL1909, Indomethacin, >=99% (TLC), UPCMLD-DP023:001, BDBM17638, CGIGDMFJXJATDK-UHFFFAOYSA-, HMS500N13, KBio1_000271, KBio2_000489, KBio2_001399, KBio2_003057, KBio2_003967, KBio2_005625, KBio2_006535, KBio3_000897, KBio3_000898, KBio3_001396, 1-(p-Chlorbenzoyl)-5-methoxy-2-methylindol-3-essigsaeure, C01EB03, M01AB01, M02AA23, S01BC01, Indomethacin - CAS 53-86-1, NINDS_000271, Bio2_000405, Bio2_000885, HMS1362I11, HMS1568H06, HMS1792I11, HMS1920F21, HMS1990I11, HMS2089N19, HMS2091N09, HMS2095H06, HMS2231J10, HMS3262K05, HMS3268A14, HMS3374F07, HMS3403I11, HMS3414N13, HMS3430L03, HMS3649K17, HMS3655O04, HMS3678N11, HMS3712H06, HMS3747K21, HMS3884E08, INDOMETHACIN [ORANGE BOOK], Indomethacin-d4(chlorobenzoyl-d4), Pharmakon1600-01500350, BCP18951, Indomethacin, >=99.0% (TLC), Tox21_113109, Tox21_201791, Tox21_300266, Tox21_500692, AC-532, CCG-40186, HB4422, INDOMETACINUM [WHO-IP LATIN], NSC757061, s1723, STL257874, AKOS000592893, Tox21_113109_1, AT13679, DB00328, Indometacin 1.0 mg/ml in Acetonitrile, KS-5255, LP00692, SDCCGSBI-0050670.P005, IDI1_000271, IDI1_002160, NCGC00015562-01, NCGC00015562-02, NCGC00015562-03, NCGC00015562-04, NCGC00015562-05, NCGC00015562-06, NCGC00015562-07, NCGC00015562-08, NCGC00015562-09, NCGC00015562-10, NCGC00015562-11, NCGC00015562-12, NCGC00015562-13, NCGC00015562-14, NCGC00015562-15, NCGC00015562-16, NCGC00015562-17, NCGC00015562-19, NCGC00015562-20, NCGC00015562-21, NCGC00015562-22, NCGC00015562-24, NCGC00015562-25, NCGC00015562-40, NCGC00024135-02, NCGC00024135-04, NCGC00024135-05, NCGC00024135-06, NCGC00024135-07, NCGC00024135-08, NCGC00024135-09, NCGC00024135-10, NCGC00024135-11, NCGC00024135-12, NCGC00024135-13, NCGC00024135-14, NCGC00024135-15, NCGC00254075-01, NCGC00259340-01, NCGC00261377-01, BI166166, BP-30207, HY-14397, NCI60_041708, O-Desmethyl-des-4-chlorobenzoylacemetacin, SBI-0050670.P004, DB-052413, AB00052022, EU-0100692, FT-0603227, I0655, NS00000217, SW196768-5, EN300-16807, Indomethacin, meets USP testing specifications, BIM-0050670.0001, C01926, D00141, S00108, AB00052022-20, AB00052022-21, AB00052022_23, AB00052022_24, L000959, Q409231, Indomethacin, Antibiotic for Culture Media Use Only, Q-201239, SR-01000000014-2, SR-01000000014-4, SR-01000000014-6, 1-(4-Chlorobenzoyl)-5-methoxy-2-met hyl-1H-indole, BRD-K57222227-001-06-1, BRD-K57222227-001-18-6, BRD-K57222227-001-27-7, SR-01000000014-10, SR-01000000014-16, Z56784896, 1-p-chlorobenzoyl-2-methyl-5-methoxyindol-3-acetic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid, 1-(p-Chlorobenzoyl)-5-methoxy-2-methylindol-3-acetic acid, 1-(p-chlorobenzyl)-5-methoxy-2-methylindole-3-acetic acid, 1-(4-chloro-benzoyl)-5-methoxy-2-methyl-3-indolyl-acetic acid, 1-(4-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acid, 1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indole-acetic acid, 1-(p-chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indol acetic acid, Indomethacin, European Pharmacopoeia (EP) Reference Standard, N-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1-H-indole-3-acetic acid, Indomethacin, United States Pharmacopeia (USP) Reference Standard, N-P-CHLOROBENZOYL-5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID, .alpha.-(1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolyl)acetic acid, [1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid #, 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid & MAP-30, 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl- (9CI), 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2 methylindol-3-yl}acetic acid, 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2methylindol-3-yl}acetic acid, Indole-3-acetic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl- (8CI), Indomethacin, Pharmaceutical Secondary Standard; Certified Reference Material, InChI=1/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)
Drug Type	Small molecule
Formula	C₁₉H₁₆ClNO₄
SMILES	CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O
InChI	1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)
InChIKey	CGIGDMFJXJATDK-UHFFFAOYSA-N
CAS Number	53-86-1
ChEMBL ID	CHEMBL6
ChEBI ID	CHEBI:49662
TTD ID	D0R1RS
Drug Bank ID	DB00328
KEGG ID	C01926
Toxicity	Organism	Test Type	Route(Dose)
	rat	LD50	intraperitoneal(165 mg/kg)
	mouse	LD50	intraperitoneal(254 mg/kg)
	rat	LD50	oral(322 mg/kg)
Structure			Download 2D MOL 3D MOL

Pair Name	Juglone, Indomethacin
Partner Name	Juglone
Disease Info	[ICD-11: 2B90]	Colon cancer		Investigative
Biological Phenomena	Induction-->Apoptosis
Gene Regulation	Up-regulation	Expression	BAD	hsa572
	Up-regulation	Expression	BAX	hsa581
	Up-regulation	Expression	BBC3	hsa27113
	Down-regulation	Expression	BCL2	hsa596
	Up-regulation	Expression	CYCS	hsa54205
	Down-regulation	Expression	NFKB1	hsa4790
	Down-regulation	Expression	PTGS2	hsa5743
	Down-regulation	Expression	TNF	hsa7124
In Vitro Model	HT-29	Colon adenocarcinoma	Homo sapiens (Human)	CVCL_0320
Result	A combination of both was shown to be more effective, suggesting that juglone may be considered for therapeutic intervention of colon cancer.

Pair Name	Juglone, Indomethacin
Partner Name	Juglone
Disease Info	[ICD-11: 2B90]	Colon cancer		Investigative
Biological Phenomena	Induction-->Apoptosis
Gene Regulation	Up-regulation	Expression	BAD	hsa572
	Up-regulation	Expression	BAX	hsa581
	Down-regulation	Expression	BCL2	hsa596
	Up-regulation	Expression	CASP3	hsa836
	Down-regulation	Expression	NFKB1	hsa4790
	Down-regulation	Expression	PTGS2	hsa5743
	Down-regulation	Expression	TNF	hsa7124
In Vivo Model	Adult male Balb/c mice were used in this study.
Result	IND and JUG reduce the inflammatory activity and induce apoptotic cell death, while JUG effectively prevents IND induced gastric ulceration. These findings establish that a combination of IND + JUG may serve as a promising treatment regimen for colon cancer.

No.	Title	Href
1	Effects of combined treatment with Indomethacin and Juglone on AOM/DSS induced colon carcinogenesis in Balb/c mice: Roles of inflammation and apoptosis. Life Sci. 2021 Jan 1;264:118657. doi: 10.1016/j.lfs.2020.118657.	`Click`
2	Indomethacin and juglone inhibit inflammatory molecules to induce apoptosis in colon cancer cells. J Biochem Mol Toxicol. 2020 Feb;34(2):e22433. doi: 10.1002/jbt.22433.	`Click`