| Pair Name | Thymoquinone, Propranolol | ||
| Phytochemical Name | Thymoquinone (PubChem CID: 10281 ) | ||
| Anticancer drug Name | Propranolol (PubChem CID: 4946 ) | ||
| Structure of Phytochemical |
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2D
MOL
3D
MOL
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| Structure of Anticancer Drug |
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2D
MOL
3D
MOL
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| Pair Name | Thymoquinone, Propranolol | |||
| Disease Info | [ICD-11: 2C23.Z] | Laryngeal cancer | Investigative | |
| Biological Phenomena | Induction-->Apoptosis | |||
| Gene Regulation | Up-regulation | Expression | BAX | hsa581 |
| Down-regulation | Expression | BCL2 | hsa596 | |
| Up-regulation | Expression | CASP3 | hsa836 | |
| Down-regulation | Expression | CCND1 | hsa595 | |
| Up-regulation | Expression | TP53 | hsa7157 | |
| Up-regulation | Expression | VEGFA | hsa7422 | |
| In Vitro Model | Hep-G2 | Hepatoblastoma | Homo sapiens (Human) | CVCL_0027 |
| Result | The effect of thymoquinone and propranolol combination on epidermoid laryngeal carcinoma cell. | |||
| No. | Title | Href |
|---|---|---|
| 1 | The effect of thymoquinone and propranolol combination on epidermoid laryngeal carcinoma cell. Eur Arch Otorhinolaryngol. 2023 Jun;280(6):2849-2858. doi: 10.1007/s00405-023-07825-0. | Click |
