InterPAD - DETAILS

MST-312, Telomerase Inhibitor IX, 368449-04-1, MST312, CHEMBL2170856, N-[3-[(2,3-dihydroxybenzoyl)amino]phenyl]-2,3-dihydroxybenzamide, Benzamide, N,N'-1,3-phenylenebis[2,3-dihydroxy-, SCHEMBL17005794, CHEBI:95003, DTXSID90439103, BDBM50396097, AKOS030590160, MS-26215, HY-120145, MST-312, >=98% (HPLC), CS-0077016, G14231, N,N'-(1,3-Phenylene)bis(2,3-dihydroxybenzamide), BRD-K19894101-001-01-6, N,N'-bis(2,3-Dihydroxybenzoyl)-1,3-phenylenediamine, Q27166764, N-[3-[[(2,3-dihydroxyphenyl)-oxomethyl]amino]phenyl]-2,3-dihydroxybenzamide

No.	Title	Href
1	Combination treatment with flavonoid morin and telomerase inhibitor MST‑312 reduces cancer stem cell traits by targeting STAT3 and telomerase. Int J Oncol. 2016 Aug;49(2):487-98. doi: 10.3892/ijo.2016.3546.	`Click`

No.

Title

Href

Combination treatment with flavonoid morin and telomerase inhibitor MST‑312 reduces cancer stem cell traits by targeting STAT3 and telomerase. Int J Oncol. 2016 Aug;49(2):487-98. doi: 10.3892/ijo.2016.3546.

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Name	MST312
PubChem CID	10385095
Molecular Weight	380.3g/mol
Synonyms	MST-312, Telomerase Inhibitor IX, 368449-04-1, MST312, CHEMBL2170856, N-[3-[(2,3-dihydroxybenzoyl)amino]phenyl]-2,3-dihydroxybenzamide, Benzamide, N,N'-1,3-phenylenebis[2,3-dihydroxy-, SCHEMBL17005794, CHEBI:95003, DTXSID90439103, BDBM50396097, AKOS030590160, MS-26215, HY-120145, MST-312, >=98% (HPLC), CS-0077016, G14231, N,N'-(1,3-Phenylene)bis(2,3-dihydroxybenzamide), BRD-K19894101-001-01-6, N,N'-bis(2,3-Dihydroxybenzoyl)-1,3-phenylenediamine, Q27166764, N-[3-[[(2,3-dihydroxyphenyl)-oxomethyl]amino]phenyl]-2,3-dihydroxybenzamide
Drug Type	Not Available
Formula	C₂₀H₁₆N₂O₆
SMILES	C1=CC(=CC(=C1)NC(=O)C2=C(C(=CC=C2)O)O)NC(=O)C3=C(C(=CC=C3)O)O
InChI	1S/C20H16N2O6/c23-15-8-2-6-13(17(15)25)19(27)21-11-4-1-5-12(10-11)22-20(28)14-7-3-9-16(24)18(14)26/h1-10,23-26H,(H,21,27)(H,22,28)
InChIKey	MIQUEZGHEJGPJB-UHFFFAOYSA-N
CAS Number	368449-04-1
ChEMBL ID	CHEMBL2170856
ChEBI ID	CHEBI:95003
Toxicity	Organism	Test Type	Route(Dose)
Structure			Download 2D MOL 3D MOL

Pair Name	Morin, MST312
Partner Name	Morin
Disease Info	[ICD-11: 2B91]	Colorectal cancer		Investigative
Gene Regulation	Up-regulation	Phosphorylation	BAD	hsa572
	Down-regulation	Cleavage	CASP3	hsa836
	Down-regulation	Phosphorylation	NFKBIA	hsa4792
	Down-regulation	Phosphorylation	STAT3	hsa6774
	Up-regulation	Phosphorylation	TP53	hsa7157
In Vitro Model	HT-29	Colon adenocarcinoma	Homo sapiens (Human)	CVCL_0320
	MDA-MB-231	Breast adenocarcinoma	Homo sapiens (Human)	CVCL_0062
	SW620	Colon adenocarcinoma	Homo sapiens (Human)	CVCL_0547
Result	Our study suggests that novel targeted-therapy can be implemented by using flavonoid morin and telomerase inhibitor MST‑312 for improved cancer prognosis.