Pair Name	Amygdalin, Cisplatin
Disease Info	[ICD-11: 2C60]	Breast cancer		Investigative
Biological Phenomena	Induction-->Apoptosis
Gene Regulation	Down-regulation	Expression	BAX	hsa581
	Down-regulation	Expression	BBC3	hsa27113
	Up-regulation	Expression	BCL2	hsa596
	Up-regulation	Expression	BCL-xL	hsa598
	Down-regulation	Cleavage	CASP9	hsa842
	Down-regulation	Phosphorylation	TP53	hsa7157
In Vitro Model	MCF-7	Invasive breast carcinoma of no special type	Homo sapiens (Human)	CVCL_0031
	MDA-MB-231	Breast adenocarcinoma	Homo sapiens (Human)	CVCL_0062
Result	Our present findings suggest that amygdalin has chemo-modulatory effect when used in co-treatment with cisplatin and is able to protect normal breast cells as well as the fibroblasts during chemotherapy treatment, indicating a strong selective chemoprotective ability and may contribute to a better quality of life for cancer patients.