Pair Name	Dihydroartemisinin, Doxorubicin
Disease Info	[ICD-11: 2C60]	Breast cancer		Investigative
Biological Phenomena	Induction-->Apoptosis
Gene Regulation	Up-regulation	Cleavage	CASP7	hsa840
	Up-regulation	Cleavage	CASP9	hsa842
	Up-regulation	Cleavage	PARP1	hsa142
In Vitro Model	MCF-7	Invasive breast carcinoma of no special type	Homo sapiens (Human)	CVCL_0031
	MDA-MB-231	Breast adenocarcinoma	Homo sapiens (Human)	CVCL_0062
	T-47D	Invasive breast carcinoma of no special type	Homo sapiens (Human)	CVCL_0553
Result	This study presented a new opportunity to enhance the effectiveness of future treatment regimens of breast cancer using DOX.

Pair Name	Dihydroartemisinin, Doxorubicin
Disease Info	[ICD-11: 2A81]	Primary effusion lymphoma		Investigative
Biological Phenomena	Induction-->Apoptosis
Gene Regulation	Up-regulation	Cleavage	CASP3	hsa836
	Up-regulation	Cleavage	CASP8	hsa841
	Up-regulation	Cleavage	CASP9	hsa842
In Vivo Model	An inhibitory effect on PEL growth was evaluated in a PEL-xenograft mouse model，DHA treatment also demonstrated an inhibitory effect on PEL cell growth in an in-vivo xenograft model.
Result	DHA is a potentially effective candidate drug for PEL treatment.