InterPAD - DETAILS

l-ascorbic acid, ascorbic acid, vitamin C, 50-81-7, L-ascorbate, Ascoltin, ascorbate, Ascorbicap, Cevitamic acid, L(+)-Ascorbic acid, Laroscorbine, Testascorbic, Allercorb, Ascorbajen, Ascorbutina, Ascorteal, Ascorvit, Cantaxin, Cebicure, Cegiolan, Celaskon, Cenetone, Cenolate, Cescorbat, Cetemican, Cevatine, Cevitamin, Citriscorb, Colascor, Concemin, Lemascorb, Proscorbin, Roscorbic, Secorbate, Viforcit, Viscorin, Vitacimin, Vitamisin, Vitascorbol, Adenex, Ascorb, Ascorin, Cantan, Cebion, Cebione, Ceglion, Cemagyl, Cemill, Cereon, Cergona, Cetamid, Cevimin, Cevital, Cevitan, Cevitex, Ciamin, Hybrin, Redoxon, Ribena, Vicelat, Vitace, Vitacee, Vitacin, Cebid, Cecon, Celin, Cevex, Cipca, Hicee, Xitix, Davitamon C, Arco-cee, Planavit C, Catavin C, Ce lent, Liqui-Cee, Vicomin C, Cee-Vite, Cevi-Bid, Natrascorb, Scorbacid, Scorbu-C, Duoscorb, C-Level, C-Vimin, Cetane-Caps TD, Cewin, C-Long, C-Quin, C-Span, Meri-C, Cee-Caps TD, Cevalin, Antiscorbic vitamin, 3-Oxo-L-gulofuranolactone, L-Lyxoascorbic acid, L-Xyloascorbic acid, Ce-Mi-Lin, Acidum ascorbicum, Antiscorbutic vitamin, Natrascorb injectable, IDO-C, Cetane-Caps TC, Acidum ascorbinicum, CE-VI-Sol, 3-Keto-L-gulofuranolactone, L-(+)-Ascorbic Acid, Kyselina askorbova, Dora-C-500, Ascor-B.I.D., Ascorbicab, (R)-5-((S)-1,2-dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one, Acido ascorbico, Acide ascorbique, Cortalex, Ferancee, Stuartinic, Tolfrinic, L-Threoascorbic acid, Caswell No. 061B, Antiscorbutic factor, FEMA No. 2109, L-3-Ketothreohexuronic acid lactone, Ascorbinsaeure, (+)-Ascorbic acid, Chromagen, Kyselina askorbova [Czech], Ascor, NCI-C54808, Ascorbicum acidum, Ferrous ascorbate, Acide ascorbique [INN-French], Acido ascorbico [INN-Spanish], Acidum ascorbicum [INN-Latin], Sodascorbate, CCRIS 57, L-threo-Hex-2-enonic acid, gamma-lactone, L-threo-Ascorbic acid, Chewcee, Citrovit, HSDB 818, Juvamine, 3-Oxo-L-gulofuranolactone (enol form), Vasc, UNII-PQ6CK8PD0R, PQ6CK8PD0R, Rovimix C, Scorbu C, EINECS 200-066-2, NSC 33832, Ascorbic acid, l-, Cetebe, Ascorbin, Ronotec 100, Ascorbyl radical, INS NO.300, DTXSID5020106, Rontex 100, CHEBI:29073, INS-300, Hex-2-enonic acid gamma-lactone, L-threo-, E-300, L-Ascorbic acid (GMP), MFCD00064328, NSC-33832, Iron(II) ascorbate, NSC-218455, component of E and C-Level, component of Endoglobin Forte, E300, DTXCID90106, Vitamin c (as ascorbic acid), (5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2,5-dihydrofuran-2-one, Ascorbic acid [USP:INN:BAN:JAN], component of Cortalex, component of Ferancee, NSC 218455, 6730-29-6, cevibid, NCGC00164357-01, Ester-C, (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one, (5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one, ASCORBIC ACID (II), ASCORBIC ACID [II], L-Ascorbic acid 1000 microg/mL in Acetonitrile, Ascorbinsaure, Kangbingfeng, 53262-66-1, Ceklin, ASCORBIC ACID (MART.), ASCORBIC ACID [MART.], Acide ascorbique (INN-French), Acido ascorbico (INN-Spanish), Acidum ascorbicum (INN-Latin), ASCORBIC ACID (USP-RS), ASCORBIC ACID [USP-RS], Parentrovite, Cell C, NSC33832, Ascorbic acid (USP:INN:BAN:JAN), Viscorin 100M, ASCORBIC ACID (EP MONOGRAPH), ASCORBIC ACID [EP MONOGRAPH], ASCORBIC ACID (USP MONOGRAPH), ASCORBIC ACID [USP MONOGRAPH], Suncoat VC 40, Acid, Ascorbic, (5R)-5-((1S)-1,2-DIHYDROXYETHYL)-3,4-DIHYDROXYFURAN-2(5H)-ONE, Ascorbicap (TN), Xyloascorbic acid, L-, Ascoltin (TN), [14C]ascorbic acid, Ascorbic acid [BAN:INN:JAN], [14C]-ascorbic acid, ascorbic acid (vit C), L-Ascorbic acid, meets USP testing specifications, 2-(1,2-Dihydroxyethyl)-4,5-dihydroxyfuran-3-one, DTXSID7048112, Ascorbinezuur, Cevitamate, Asorbicap, Clairfore, CleanFlex, L-lyxoascorbate, L-xyloascorbate, .Ascorbinsaure, New Clairfore, vitamine C, Vitamina C, 3eka, Ester C, (+)-ascorbate, L(+)-ascorbate, L-threo-hex-2-enono-1,4-lactone, HICELl, L-Ascorbic acid, free radical form, L-(+)-ascorbate, Vitamin C,(S), E 300, Ascorbic Acid1505, NEO-VALDRIN, VITA RICH, Dr Cellapy SR Premium, VIT C, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4,5-dihydroxyfuran-3-one, Prestwick3_000325, L-Ascorbic acid, 99%, ASCOR (TN), SCHEMBL785, hex-1-enofuranos-3-ulose, bmse000182, VITAMIN C [VANDF], Vitamin C (Ascorbic acid), ASCORBIC ACID [MI], SCHEMBL4430, ASCORBIC ACID [FCC], ASCORBIC ACID [INN], ASCORBIC ACID [JAN], L-Ascorbic acid, FCC, FG, L-Ascorbic Acid, Free Acid, ASCORBIC ACID [FHFI], ASCORBIC ACID [HSDB], BSPBio_000329, (r)-5-(1,2-dihydroxy-ethyl)-3,4-dihydroxy-5h-furan-2-one, MLS002153776, AROMACURA SHOWER FILTER, ASCORBIC ACID [VANDF], CHEMBL40274, L-Ascorbic acid, cell culture, BPBio1_000363, GTPL4532, GTPL4781, L-Ascorbic acid, reagent grade, ASCORBIC ACID [WHO-DD], ASCORBIC ACID [WHO-IP], L-Ascorbic acid, >=99.0%, CHEBI:22652, HY-B0166G, DTXCID50820452, DTXSID50986567, Ascorbic acid (JP17/USP/INN), CHEBI:176783, DTXSID801344780, HMS2096A11, HMS2231N16, HMS3713A11, L-Ascorbic acid ACS reagent grade, (2R)-2-[(1S)-1,2-Dihydroxyethyl]-4,5-dihydroxy-furan-3-one, ASCORBIC ACID [ORANGE BOOK], BCP27915, HY-B0166, L-Threoascorbic acid,Antiscorbutic factor,Vitamin C;(R)-5-((S)-1,2-Dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one, Tox21_110315, Tox21_112104, Tox21_202127, Tox21_302958, gamma-lactone L-threo-Hex-2-enonate, HB1238, L-Ascorbic acid, analytical standard, L-Ascorbic acid, AR, >=99.5%, s3114, AKOS016843589, Tox21_112104_1, 1ST1523, CCG-207946, DB00126, L-Ascorbic acid, mixt. with vitamin B, ACIDUM ASCORBICUM [WHO-IP LATIN], gamma-lactone L-threo-Hex-2-enonic acid, L-Ascorbic acid, ACS reagent, >=99%, NCGC00091517-01, NCGC00091517-02, NCGC00091517-03, NCGC00091517-06, NCGC00188972-01, NCGC00256504-01, NCGC00259676-01, BP-12831, SMR001233160, L-Ascorbic acid, plant cell culture tested, L-Ascorbic acid, reagent grade, crystalline, A0537, AB00376923, Ascorbic Acid (L-Ascorbic Acid; Vitamin C), CS-0626121, NS00001126, SW198791-2, L-Ascorbic acid, BioUltra, >=99.5% (RT), L-Ascorbic acid, tested according to Ph.Eur., C00072, D00018, E80759, EN300-708766, L-Ascorbic acid, p.a., ACS reagent, 99.0%, 2,3-DEHYDRO-L-THREO-HEXONO-1,4-LACTONE, AB00376923_04, AB00376923_05, Celladix C.E.F ADVANCED BRIGHTENING AMPOULE, L-Ascorbic acid, JIS special grade, >=99.0%, L-Ascorbic acid, Vetec(TM) reagent grade, 99%, L-Ascorbic acid, BioXtra, >=99.0%, crystalline, Q199678, 2-(1,2-dihydroxyethyl)-4,5-dihydroxy-furan-3-one, L-Ascorbic acid, puriss. p.a., >=99.0% (RT), Q27101942, 47A605F0-4187-47A8-B0CE-F9E7DA1B0076, L-Ascorbic acid, p.a., ACS reagent, reag. ISO, 99.7%, Ascorbic acid, British Pharmacopoeia (BP) Reference Standard, Ascorbic acid, European Pharmacopoeia (EP) Reference Standard, L-Ascorbic acid, certified reference material, TraceCERT(R), L-Ascorbic acid, powder, cell culture tested, gamma-irradiated, Ascorbic acid, United States Pharmacopeia (USP) Reference Standard, (5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one (non-preferred name), L-Ascorbic acid, anhydrous, free-flowing, Redi-Dri(TM), ACS reagent, >=99%, L-Ascorbic acid, suitable for cell culture, suitable for plant cell culture, >=98%, L-Ascorbic acid, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., 99.7-100.5% (oxidimetric)

Name	Ascorbic Acid
PubChem CID	54670067
Molecular Weight	176.12g/mol
Synonyms	l-ascorbic acid, ascorbic acid, vitamin C, 50-81-7, L-ascorbate, Ascoltin, ascorbate, Ascorbicap, Cevitamic acid, L(+)-Ascorbic acid, Laroscorbine, Testascorbic, Allercorb, Ascorbajen, Ascorbutina, Ascorteal, Ascorvit, Cantaxin, Cebicure, Cegiolan, Celaskon, Cenetone, Cenolate, Cescorbat, Cetemican, Cevatine, Cevitamin, Citriscorb, Colascor, Concemin, Lemascorb, Proscorbin, Roscorbic, Secorbate, Viforcit, Viscorin, Vitacimin, Vitamisin, Vitascorbol, Adenex, Ascorb, Ascorin, Cantan, Cebion, Cebione, Ceglion, Cemagyl, Cemill, Cereon, Cergona, Cetamid, Cevimin, Cevital, Cevitan, Cevitex, Ciamin, Hybrin, Redoxon, Ribena, Vicelat, Vitace, Vitacee, Vitacin, Cebid, Cecon, Celin, Cevex, Cipca, Hicee, Xitix, Davitamon C, Arco-cee, Planavit C, Catavin C, Ce lent, Liqui-Cee, Vicomin C, Cee-Vite, Cevi-Bid, Natrascorb, Scorbacid, Scorbu-C, Duoscorb, C-Level, C-Vimin, Cetane-Caps TD, Cewin, C-Long, C-Quin, C-Span, Meri-C, Cee-Caps TD, Cevalin, Antiscorbic vitamin, 3-Oxo-L-gulofuranolactone, L-Lyxoascorbic acid, L-Xyloascorbic acid, Ce-Mi-Lin, Acidum ascorbicum, Antiscorbutic vitamin, Natrascorb injectable, IDO-C, Cetane-Caps TC, Acidum ascorbinicum, CE-VI-Sol, 3-Keto-L-gulofuranolactone, L-(+)-Ascorbic Acid, Kyselina askorbova, Dora-C-500, Ascor-B.I.D., Ascorbicab, (R)-5-((S)-1,2-dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one, Acido ascorbico, Acide ascorbique, Cortalex, Ferancee, Stuartinic, Tolfrinic, L-Threoascorbic acid, Caswell No. 061B, Antiscorbutic factor, FEMA No. 2109, L-3-Ketothreohexuronic acid lactone, Ascorbinsaeure, (+)-Ascorbic acid, Chromagen, Kyselina askorbova [Czech], Ascor, NCI-C54808, Ascorbicum acidum, Ferrous ascorbate, Acide ascorbique [INN-French], Acido ascorbico [INN-Spanish], Acidum ascorbicum [INN-Latin], Sodascorbate, CCRIS 57, L-threo-Hex-2-enonic acid, gamma-lactone, L-threo-Ascorbic acid, Chewcee, Citrovit, HSDB 818, Juvamine, 3-Oxo-L-gulofuranolactone (enol form), Vasc, UNII-PQ6CK8PD0R, PQ6CK8PD0R, Rovimix C, Scorbu C, EINECS 200-066-2, NSC 33832, Ascorbic acid, l-, Cetebe, Ascorbin, Ronotec 100, Ascorbyl radical, INS NO.300, DTXSID5020106, Rontex 100, CHEBI:29073, INS-300, Hex-2-enonic acid gamma-lactone, L-threo-, E-300, L-Ascorbic acid (GMP), MFCD00064328, NSC-33832, Iron(II) ascorbate, NSC-218455, component of E and C-Level, component of Endoglobin Forte, E300, DTXCID90106, Vitamin c (as ascorbic acid), (5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2,5-dihydrofuran-2-one, Ascorbic acid [USP:INN:BAN:JAN], component of Cortalex, component of Ferancee, NSC 218455, 6730-29-6, cevibid, NCGC00164357-01, Ester-C, (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one, (5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one, ASCORBIC ACID (II), ASCORBIC ACID [II], L-Ascorbic acid 1000 microg/mL in Acetonitrile, Ascorbinsaure, Kangbingfeng, 53262-66-1, Ceklin, ASCORBIC ACID (MART.), ASCORBIC ACID [MART.], Acide ascorbique (INN-French), Acido ascorbico (INN-Spanish), Acidum ascorbicum (INN-Latin), ASCORBIC ACID (USP-RS), ASCORBIC ACID [USP-RS], Parentrovite, Cell C, NSC33832, Ascorbic acid (USP:INN:BAN:JAN), Viscorin 100M, ASCORBIC ACID (EP MONOGRAPH), ASCORBIC ACID [EP MONOGRAPH], ASCORBIC ACID (USP MONOGRAPH), ASCORBIC ACID [USP MONOGRAPH], Suncoat VC 40, Acid, Ascorbic, (5R)-5-((1S)-1,2-DIHYDROXYETHYL)-3,4-DIHYDROXYFURAN-2(5H)-ONE, Ascorbicap (TN), Xyloascorbic acid, L-, Ascoltin (TN), [14C]ascorbic acid, Ascorbic acid [BAN:INN:JAN], [14C]-ascorbic acid, ascorbic acid (vit C), L-Ascorbic acid, meets USP testing specifications, 2-(1,2-Dihydroxyethyl)-4,5-dihydroxyfuran-3-one, DTXSID7048112, Ascorbinezuur, Cevitamate, Asorbicap, Clairfore, CleanFlex, L-lyxoascorbate, L-xyloascorbate, .Ascorbinsaure, New Clairfore, vitamine C, Vitamina C, 3eka, Ester C, (+)-ascorbate, L(+)-ascorbate, L-threo-hex-2-enono-1,4-lactone, HICELl, L-Ascorbic acid, free radical form, L-(+)-ascorbate, Vitamin C,(S), E 300, Ascorbic Acid1505, NEO-VALDRIN, VITA RICH, Dr Cellapy SR Premium, VIT C, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4,5-dihydroxyfuran-3-one, Prestwick3_000325, L-Ascorbic acid, 99%, ASCOR (TN), SCHEMBL785, hex-1-enofuranos-3-ulose, bmse000182, VITAMIN C [VANDF], Vitamin C (Ascorbic acid), ASCORBIC ACID [MI], SCHEMBL4430, ASCORBIC ACID [FCC], ASCORBIC ACID [INN], ASCORBIC ACID [JAN], L-Ascorbic acid, FCC, FG, L-Ascorbic Acid, Free Acid, ASCORBIC ACID [FHFI], ASCORBIC ACID [HSDB], BSPBio_000329, (r)-5-(1,2-dihydroxy-ethyl)-3,4-dihydroxy-5h-furan-2-one, MLS002153776, AROMACURA SHOWER FILTER, ASCORBIC ACID [VANDF], CHEMBL40274, L-Ascorbic acid, cell culture, BPBio1_000363, GTPL4532, GTPL4781, L-Ascorbic acid, reagent grade, ASCORBIC ACID [WHO-DD], ASCORBIC ACID [WHO-IP], L-Ascorbic acid, >=99.0%, CHEBI:22652, HY-B0166G, DTXCID50820452, DTXSID50986567, Ascorbic acid (JP17/USP/INN), CHEBI:176783, DTXSID801344780, HMS2096A11, HMS2231N16, HMS3713A11, L-Ascorbic acid ACS reagent grade, (2R)-2-[(1S)-1,2-Dihydroxyethyl]-4,5-dihydroxy-furan-3-one, ASCORBIC ACID [ORANGE BOOK], BCP27915, HY-B0166, L-Threoascorbic acid,Antiscorbutic factor,Vitamin C;(R)-5-((S)-1,2-Dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one, Tox21_110315, Tox21_112104, Tox21_202127, Tox21_302958, gamma-lactone L-threo-Hex-2-enonate, HB1238, L-Ascorbic acid, analytical standard, L-Ascorbic acid, AR, >=99.5%, s3114, AKOS016843589, Tox21_112104_1, 1ST1523, CCG-207946, DB00126, L-Ascorbic acid, mixt. with vitamin B, ACIDUM ASCORBICUM [WHO-IP LATIN], gamma-lactone L-threo-Hex-2-enonic acid, L-Ascorbic acid, ACS reagent, >=99%, NCGC00091517-01, NCGC00091517-02, NCGC00091517-03, NCGC00091517-06, NCGC00188972-01, NCGC00256504-01, NCGC00259676-01, BP-12831, SMR001233160, L-Ascorbic acid, plant cell culture tested, L-Ascorbic acid, reagent grade, crystalline, A0537, AB00376923, Ascorbic Acid (L-Ascorbic Acid; Vitamin C), CS-0626121, NS00001126, SW198791-2, L-Ascorbic acid, BioUltra, >=99.5% (RT), L-Ascorbic acid, tested according to Ph.Eur., C00072, D00018, E80759, EN300-708766, L-Ascorbic acid, p.a., ACS reagent, 99.0%, 2,3-DEHYDRO-L-THREO-HEXONO-1,4-LACTONE, AB00376923_04, AB00376923_05, Celladix C.E.F ADVANCED BRIGHTENING AMPOULE, L-Ascorbic acid, JIS special grade, >=99.0%, L-Ascorbic acid, Vetec(TM) reagent grade, 99%, L-Ascorbic acid, BioXtra, >=99.0%, crystalline, Q199678, 2-(1,2-dihydroxyethyl)-4,5-dihydroxy-furan-3-one, L-Ascorbic acid, puriss. p.a., >=99.0% (RT), Q27101942, 47A605F0-4187-47A8-B0CE-F9E7DA1B0076, L-Ascorbic acid, p.a., ACS reagent, reag. ISO, 99.7%, Ascorbic acid, British Pharmacopoeia (BP) Reference Standard, Ascorbic acid, European Pharmacopoeia (EP) Reference Standard, L-Ascorbic acid, certified reference material, TraceCERT(R), L-Ascorbic acid, powder, cell culture tested, gamma-irradiated, Ascorbic acid, United States Pharmacopeia (USP) Reference Standard, (5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one (non-preferred name), L-Ascorbic acid, anhydrous, free-flowing, Redi-Dri(TM), ACS reagent, >=99%, L-Ascorbic acid, suitable for cell culture, suitable for plant cell culture, >=98%, L-Ascorbic acid, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., 99.7-100.5% (oxidimetric)
Drug Type	Small molecule
Formula	C₆H₈O₆
SMILES	C(C(C1C(=C(C(=O)O1)O)O)O)O
InChI	1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
InChIKey	CIWBSHSKHKDKBQ-JLAZNSOCSA-N
CAS Number	50-81-7
ChEMBL ID	CHEMBL40274
ChEBI ID	CHEBI:29073
TTD ID	D01CWN
Drug Bank ID	DB00126
KEGG ID	C00072
Toxicity	Organism	Test Type	Route(Dose)
	rat	LD50	intraperitoneal(165 mg/kg)
	mouse	LD50	intraperitoneal(254 mg/kg)
	rat	LD50	oral(322 mg/kg)
Structure			Download 2D MOL 3D MOL

Pair Name	Menadione, Ascorbic Acid
Partner Name	Menadione
Disease Info	[ICD-11: 2A00]	Glioblastoma multiforme		Investigative
Biological Phenomena	Induction-->Oxidative Stress
Gene Regulation	Down-regulation	Expression	BECN1	hsa8678
	Up-regulation	Activity	BECN1	hsa8678
	Up-regulation	Phosphorylation	PRKAA1	hsa5562
	Down-regulation	Expression	RHEB	hsa6009
	Down-regulation	Expression	SQSTM1	hsa8878
	Up-regulation	Phosphorylation	ULK1	hsa8408
In Vitro Model	U-251MG	Astrocytoma	Homo sapiens (Human)	CVCL_0021
Result	These results suggest that AA+MD or MD treatment in combination with autophagy inducers could be further investigated as a novel approach for glioblastoma therapy.