InterPAD - DETAILS

pyridoxine, 65-23-6, Pyridoxol, Pyridoxin, 3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine, Adermine, Gravidox, Hydoxin, Pyridoxolum, 3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-, 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol, 5-Hydroxy-6-methyl-3,4-pyridinedimethanol, Pyridoxinum, Piridossina, Piridoxina, Piridossina [DCIT], 3-Hydroxy-4,5-dimethylol-alpha-picoline, Pyridoxinum [INN-Latin], 12001-77-3, Piridoxina [INN-Spanish], Hexabione, (5-Hydroxy-6-methylpyridine-3,4-diyl)dimethanol, 2-Methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, 2-Picoline-4,5-dimethanol, 3-hydroxy-, Pyridoxine [INN:BAN], 2-Methyl-3-hydroxy-4,5-di(hydroxymethyl)pyridine, 2-Methyl-4,5-bis(hydroxymethyl)-3-hydroxypyridine, CHEBI:16709, EINECS 200-603-0, 4,5-bis(hydroxymethyl)-2-methyl-pyridin-3-ol, UNII-KV2JZ1BI6Z, KV2JZ1BI6Z, VitaminB6, Vitamin V6, Pyridoxin hydrochloride, vitamin B-6, 2-methyl-3-hydroxy-4,5-dihydroxymethylpyridine, NSC-759148, DTXSID4023541, Pyridoxine free base, 2-Methyl-3-hydroxy-4,5-dihydroxymethyl-pyridin [German], 4,5-Bis(hydroxymethyl)-2-methyl-3-pyridinol, Prestwick0_000623, Prestwick1_000623, Prestwick2_000623, Prestwick3_000623, Adermin hydrochloride, 2-Methyl-3-hydroxy-4,5-dihydroxymethyl-pyridin, TimTec1_000657, Oprea1_061614, BSPBio_000586, CBDivE_015627, SPBio_002805, DTXCID903541, BPBio1_000646, Pyridoxine hydrogen chloride, Pyridoxine (INN), M.V.I.-12, STK177324, 65-23-6 (FREE BASE), 2-methyl-3-hydroxy-4,5-bis(hydroxy-methyl) pyridine, 3-hydroxy-2-Picoline-4,5-dimethanol, NSC 759148, DB00165, CAS-58-56-0, SMP2_000230, NCGC00016261-01, NCGC00016261-03, PYRIDOXINE [INN], Pyridoxinum (INN-Latin), Piridoxina (INN-Spanish), C00314, AC-907/25014218, Adermin, Bezatin, Pirivitol, Infuvite Pediatric, CAS-65-23-6, PN, NSC36225, Pyridoxine (Vit B6), SR-05000001644, NCGC00164317-01, M.V.I.-12 Lyophilized, pyridoxina, Pridoxine, vitaminum b6, Beesix (Salt/Mix), nchembio.93-comp1, Becilan (Salt/Mix), Benadon (Salt/Mix), Hexobion (Salt/Mix), Vitamin B6 (TN), Pyridoxol; Vitamin B6, Pyridoxine, >=98%, Hexabetalin (Salt/Mix), PYRIDOXINE [MI], Vitamin b6,hydrochloride, LS-134393, PYRIDOXINE [VANDF], bmse000288, SCHEMBL3506, CHEMBL1364, PYRIDOXINE [WHO-DD], BIDD:PXR0180, VITAMIN B6 [VANDF], P5669_SIGMA, PYRIDOXINE [ORANGE BOOK], A11HA02, NSC36225 (HCL), Pyridoxol, Vitamin B6, Gravidox, AIDS006784, HMS2093L07, KUC106691N, Pharmakon1600-01505453, AIDS-006784, BCP27975, HY-B1328, Tox21_113644, Tox21_300365, BBL005552, BDBM50103505, c1302, MFCD00006335, NSC759148, s3980, ZINC00049154, AKOS005410791, Tox21_113644_1, CCG-213453, CS-W019950, 2-methyl-4,5-dimethylol-pyridin-3-ol, Vitamin B6 100 microg/mL in Methanol, NCGC00016261-02, NCGC00016261-04, NCGC00016261-05, NCGC00016261-08, NCGC00164317-02, NCGC00254340-01, AC-14512, DS-11013, 58-56-0 (HCL), KSC-11-207-23, SBI-0206844.P001, 3-Hydroxy-4,5-dimethylol-.alpha.-picoline, DB-073595, AM20070169, FT-0631288, FT-0674200, NS00004187, EN300-39851, 4,5-bis(hydroxymethyl)-2-methylpyridine-3-ol, D08454, O10129, 4,5-Bis(hydroxymethyl)-2-methyl-3-pyridinol #, A835033, Q423746, Q-201646, SR-05000001644-1, SR-05000001644-3, 2B3E07D2-E4CC-4CC5-B085-6070BA01F9F0, Z382721012, 2-methyl-3-hydroxy-4-hydroxymethyl-5-hydroxymethyl pyridine, InChI=1/C8H11NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,10-12H,3-4H2,1H

Name	Pyridoxine
PubChem CID	1054
Molecular Weight	169.18g/mol
Synonyms	pyridoxine, 65-23-6, Pyridoxol, Pyridoxin, 3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine, Adermine, Gravidox, Hydoxin, Pyridoxolum, 3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-, 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol, 5-Hydroxy-6-methyl-3,4-pyridinedimethanol, Pyridoxinum, Piridossina, Piridoxina, Piridossina [DCIT], 3-Hydroxy-4,5-dimethylol-alpha-picoline, Pyridoxinum [INN-Latin], 12001-77-3, Piridoxina [INN-Spanish], Hexabione, (5-Hydroxy-6-methylpyridine-3,4-diyl)dimethanol, 2-Methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, 2-Picoline-4,5-dimethanol, 3-hydroxy-, Pyridoxine [INN:BAN], 2-Methyl-3-hydroxy-4,5-di(hydroxymethyl)pyridine, 2-Methyl-4,5-bis(hydroxymethyl)-3-hydroxypyridine, CHEBI:16709, EINECS 200-603-0, 4,5-bis(hydroxymethyl)-2-methyl-pyridin-3-ol, UNII-KV2JZ1BI6Z, KV2JZ1BI6Z, VitaminB6, Vitamin V6, Pyridoxin hydrochloride, vitamin B-6, 2-methyl-3-hydroxy-4,5-dihydroxymethylpyridine, NSC-759148, DTXSID4023541, Pyridoxine free base, 2-Methyl-3-hydroxy-4,5-dihydroxymethyl-pyridin [German], 4,5-Bis(hydroxymethyl)-2-methyl-3-pyridinol, Prestwick0_000623, Prestwick1_000623, Prestwick2_000623, Prestwick3_000623, Adermin hydrochloride, 2-Methyl-3-hydroxy-4,5-dihydroxymethyl-pyridin, TimTec1_000657, Oprea1_061614, BSPBio_000586, CBDivE_015627, SPBio_002805, DTXCID903541, BPBio1_000646, Pyridoxine hydrogen chloride, Pyridoxine (INN), M.V.I.-12, STK177324, 65-23-6 (FREE BASE), 2-methyl-3-hydroxy-4,5-bis(hydroxy-methyl) pyridine, 3-hydroxy-2-Picoline-4,5-dimethanol, NSC 759148, DB00165, CAS-58-56-0, SMP2_000230, NCGC00016261-01, NCGC00016261-03, PYRIDOXINE [INN], Pyridoxinum (INN-Latin), Piridoxina (INN-Spanish), C00314, AC-907/25014218, Adermin, Bezatin, Pirivitol, Infuvite Pediatric, CAS-65-23-6, PN, NSC36225, Pyridoxine (Vit B6), SR-05000001644, NCGC00164317-01, M.V.I.-12 Lyophilized, pyridoxina, Pridoxine, vitaminum b6, Beesix (Salt/Mix), nchembio.93-comp1, Becilan (Salt/Mix), Benadon (Salt/Mix), Hexobion (Salt/Mix), Vitamin B6 (TN), Pyridoxol; Vitamin B6, Pyridoxine, >=98%, Hexabetalin (Salt/Mix), PYRIDOXINE [MI], Vitamin b6,hydrochloride, LS-134393, PYRIDOXINE [VANDF], bmse000288, SCHEMBL3506, CHEMBL1364, PYRIDOXINE [WHO-DD], BIDD:PXR0180, VITAMIN B6 [VANDF], P5669_SIGMA, PYRIDOXINE [ORANGE BOOK], A11HA02, NSC36225 (HCL), Pyridoxol, Vitamin B6, Gravidox, AIDS006784, HMS2093L07, KUC106691N, Pharmakon1600-01505453, AIDS-006784, BCP27975, HY-B1328, Tox21_113644, Tox21_300365, BBL005552, BDBM50103505, c1302, MFCD00006335, NSC759148, s3980, ZINC00049154, AKOS005410791, Tox21_113644_1, CCG-213453, CS-W019950, 2-methyl-4,5-dimethylol-pyridin-3-ol, Vitamin B6 100 microg/mL in Methanol, NCGC00016261-02, NCGC00016261-04, NCGC00016261-05, NCGC00016261-08, NCGC00164317-02, NCGC00254340-01, AC-14512, DS-11013, 58-56-0 (HCL), KSC-11-207-23, SBI-0206844.P001, 3-Hydroxy-4,5-dimethylol-.alpha.-picoline, DB-073595, AM20070169, FT-0631288, FT-0674200, NS00004187, EN300-39851, 4,5-bis(hydroxymethyl)-2-methylpyridine-3-ol, D08454, O10129, 4,5-Bis(hydroxymethyl)-2-methyl-3-pyridinol #, A835033, Q423746, Q-201646, SR-05000001644-1, SR-05000001644-3, 2B3E07D2-E4CC-4CC5-B085-6070BA01F9F0, Z382721012, 2-methyl-3-hydroxy-4-hydroxymethyl-5-hydroxymethyl pyridine, InChI=1/C8H11NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,10-12H,3-4H2,1H
Drug Type	Small molecule
Formula	C₈H₁₁NO₃
SMILES	CC1=NC=C(C(=C1O)CO)CO
InChI	1S/C8H11NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,10-12H,3-4H2,1H3
InChIKey	LXNHXLLTXMVWPM-UHFFFAOYSA-N
CAS Number	65-23-6
ChEMBL ID	CHEMBL1364
ChEBI ID	CHEBI:16709
TTD ID	D0B8JD
Drug Bank ID	DB00165
KEGG ID	C00314
Toxicity	Organism	Test Type	Route(Dose)
	rat	LD50	intraperitoneal(165 mg/kg)
	mouse	LD50	intraperitoneal(254 mg/kg)
	rat	LD50	oral(322 mg/kg)
Structure			Download 2D MOL 3D MOL

Pair Name	Curcumin, Pyridoxine
Partner Name	Curcumin
Disease Info	[ICD-11: 2B91]	Colorectal cancer		Investigative
Gene Regulation	Down-regulation	Phosphorylation	CTNNB1	hsa1499
	Down-regulation	Phosphorylation	PIK3CA	hsa5290
	Down-regulation	Phosphorylation	RELA	hsa5970
In Vivo Model	Male FVB mice (4 weeks old) were used in this study.
Result	C + B is superior to either agent alone in preventing obesity-promoted colorectal carcinogenesis. Augmented suppression of procancerous signaling pathways may be the means by which this augmentation occurs.