| Name | GingerenoneA | ||
| PubChem CID | / | ||
| Herb ID | HBIN027660 | ||
| Structure | 
|
Download
2D
MOL
3D
MOL
|
|
| Chineses Pinyin | ShengJiang | ||
| Use Part | Fresh rhizome | ||
| Habitat | SiChuan, GuiZhou, HuBei, GuangDong, GuangXi | ||
| Flavor | Pungent | ||
| Meridian Tropism | Lung; Spleen; Stomach | ||
| Species |
>Kingdom: Viridiplantae
-->Phylum: Streptophyta
-->Class: Equisetopsida
-->Order: Zingiberales
-->Family: Zingiberaceae
-->Genus: Zingiber
-->Species: Zingiber officinale
|
||
| Pair Name | GingerenoneA, Dexamethasone | |||
| Partner Name | Dexamethasone | |||
| Disease Info | [ICD-11: 2B33.3] | Acute lymphoblastic leukemia | Investigative | |
| Biological Phenomena | Induction-->Apoptosis | |||
| Gene Regulation | Up-regulation | Expression | CDKN1A | hsa1026 |
| Down-regulation | Expression | FASN | hsa2194 | |
| Up-regulation | Expression | MDM2 | hsa4193 | |
| Up-regulation | Expression | TP53 | hsa7157 | |
| In Vitro Model | CCRF-CEM | Childhood T acute lymphoblastic leukemia | Homo sapiens (Human) | CVCL_0207 |
| NALM-6 | Adult B acute lymphoblastic leukemia | Homo sapiens (Human) | CVCL_0092 | |
| RN95 | B‐ALL subline derived from a 12‐year‐old Iranian girl with relapsed ALL | Homo sapiens (Human) | N.A. | |
| Result | Our findings may provide novel strategies for therapeutic intervention to ameliorate pALL outcomes. | |||
