Pair Name	Ginger extract, Doxorubicin
Disease Info	[ICD-11: 2A00-2F9Z]	Solid tumour or cancer		Investigative
Biological Phenomena	Induction-->Apoptosis
Gene Regulation	Down-regulation	Expression	CCND1	hsa595
	Down-regulation	Expression	NFKB1	hsa4790
	Up-regulation	Phosphorylation	PRKAA1	hsa5562
	Up-regulation	Expression	TP53	hsa7157
In Vivo Model	1×10⁶ EAC cells were implanted subcutaneously into the right thigh of the lower limb of mice.
Result	AMPK pathway and cyclin D1 gene expression could be a molecular therapeutic target for the anticancer effect of GE in mice bearing SEC. Combining GE and DOX revealed a greater efficacy as anticancer therapeutic regimen.