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  1. General Info
  2. Effects Info
  3. Reference
Drug Details
01. General Information
Name Selenium
PubChem CID 6326970
Molecular Weight 78.97g/mol
Synonyms

7782-49-2, Se, Selenium, Selenium hydride, SELENIUM ATOM, Elemental selenium, Selenium elemental, Selenium, elemental, Selen, Selenium dihydride, Selenium metallicum, SELENIUM POWDER, CI 77805, Dihydrogen monoselenide, C.I. 77805, SELENIUM78, MFCD00134090, Hydrogen selenide, anhydrous, H6241UJ22B, Vandex, Gray selenium, Selenium base, Selenium dust, Colloidal selenium, Selen [Polish], elenium, elemental; Vandex;, Selenium, metallic, Selenium, colloidal, Caswell No. 732, selenio, Selenium anhydride, Electronic E-2, CCRIS 4250, HSDB 4493, EINECS 231-957-4, UN2658, Hydrogen selenide (H2Se), EPA Pesticide Chemical Code 072001, Selenium Standard: Se @ 1000 microg/mL in 5% HNO3, Selenium Standard: Se @ 10000 microg/mL in 5% HNO3, Selenium AA Standard: Se @ 1000 microg/mL in 5% HNO3, Selenium metal, UNII-H6241UJ22B, HSDB 548, Selenium, powder, Selenium (Powder), EINECS 231-978-9, Selenium shot, 4N, selenium (hexagonal), UN2202, UN3283, selenium (iv) hydride, HYDROGEN SELENID, B-TRAXIM SE, SELENIUM [MI], SELENIUM [VANDF], Selenium hydride (SeH2), SELENIUM [MART.], 34Se, SELENIUM [WHO-DD], UNII-V91P54KPAM, EC 231-957-4, Selenium, powder, 99+%, Selenium compound, n.o.s., Selenium powder, -200 mesh, Selenium powder, -325 mesh, SELSAF 2000, HYDROGEN SELENIDE [MI], Selenium, p.a., 99.5%, CHEMBL1235891, DTXSID9021261, CHEBI:27568, HSDB 6909, Selenium Nanopowder in aq. media, SELENIUM METALLICUM [HPUS], SELENIUM, ELEMENTAL [HSDB], powder,99.9% metals basis,200mesh, DB11135, NSC-605850, NSC-605851, NSC-605852, N725, Q876, Selenium, pellets, < 5mm, >=99.999%, E1457, NS00099723, Selenium ingot/button, ~38mm (1.5in) dia, C01529, Selenium - Se @ 1000 microg/mL in 5% HNO3, Selenium - Se @ 1000 microg/g in Hydrocarbon Oil, Selenium powder [UN2658] [Keep away from food], Selenium shot, amorphous, 1-5mm (0.04-0.20in), Selenium Standard: Se @ 10 microg/mL in 2% HNO3, Selenium, foil, 25x25mm, thickness 3mm, 99.95%, Hydrogen selenide, anhydrous [UN2202] [Poison gas], S008000000, Selenium, shots, 99.99999% (7N), diameter 2-4 mm, Selenium Standard: Se @ 1000 microg/g in Hydrocarbon Oil, Selenium, pellets, <5 mm, >=99.99% trace metals basis, Selenium, powder, -100 mesh, >=99.5% trace metals basis, Selenium, powder, -100 mesh, 99.99% trace metals basis, Selenium Hollow Cathode Lamp: 2.0" Diameter, 4-pin, Cableless, Selenium Hollow Cathode Lamp: 1.5" Diameter, 2-pin, Non-Coded, Selenium Hollow Cathode Lamp: 2.0" Diameter, 9-pin, Non-Coded, Selenium compound, n.o.s. [UN3283] [Poison, Keep away from food], Selenium, lump, 3 mm max. lump size, weight 100 g, high purity 99.999%, Selenium, lump, 3 mm max. lump size, weight 20 g, high purity 99.999%, Selenium, lump, 3 mm max. lump size, weight 50 g, high purity 99.999%, Selenium, pellets, <5 mm particle size, >=99.999% trace metals basis, Sulfur-Free Selenium Standard: Se @ 1000 microg/g in Hydrocarbon Oil, Selenium shot, amorphous, 2-6mm (0.08-0.2in), Puratronic(R), 99.999% (metals basis), Selenium, powder, 250 max. part. size (micron), purity 99.95%, weight 100 g, Selenium, powder, 250 max. part. size (micron), weight 50 g, purity 99.95%, Selenium, powder, max. particle size 250 micron, weight 200 g, purity 99.95%, Selenium, rod, 99.9999% (6N), diameter 20 mm, length 55 mm, approx. 74g, Selenium, rod, 99.99999% (7N), diameter 20 mm, length 55 mm, approx. 74 g, Se0

Drug Type Small molecule
Formula Se
SMILES [Se]
InChI 1S/Se
InChIKey BUGBHKTXTAQXES-UHFFFAOYSA-N
CAS Number 7782-49-2
ChEMBL ID CHEMBL1235891
ChEBI ID CHEBI:27568
TTD ID D0X2AU
Drug Bank ID DB11135
KEGG ID C01529
Toxicity Organism Test Type Route(Dose)
rat LD50 intraperitoneal(165 mg/kg)
mouse LD50 intraperitoneal(254 mg/kg)
rat LD50 oral(322 mg/kg)
Structure 2D-img
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2D MOL 3D MOL
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Decreasing Drug Toxicity
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Combination Pair ID: 554
Pair Name Sulforaphane, Selenium
Partner Name Sulforaphane
Disease Info [ICD-11: 2B90] Colon cancer Investigative
Biological Phenomena Induction-->Protection oxidative damage
Gene Regulation Up-regulation Expression NFE2L2 hsa4780
Up-regulation Expression TXNRD1 hsa7296
In Vitro Model CCD-841CoN Healthy Homo sapiens (Human) CVCL_2871
Result Combined SFN and Se treatment synergistically upregulated TrxR-1, which plays a significant role in maintaining intracellular redox homeostasis and contributed to the SFN-induced protection against free radical-mediated oxidative damage in normal colonic cells.
03. Reference
No. Title Href
1 Synergy between sulforaphane and selenium in protection against oxidative damage in colonic CCD841 cells. Nutr Res. 2015 Jul;35(7):610-7. doi: 10.1016/j.nutres.2015.05.011. Click
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