| Pair Name | Raddeanin A, Cisplatin | ||
| Phytochemical Name | Raddeanin A (PubChem CID: 174742 ) | ||
| Anticancer drug Name | Cisplatin (PubChem CID: 5702198 ) | ||
| Structure of Phytochemical |
|
Download
2D
MOL
3D
MOL
|
|
| Structure of Anticancer Drug |
|
Download
2D
MOL
3D
MOL
|
|
| Pair Name | Raddeanin A, Cisplatin | |||
| Disease Info | [ICD-11: 2C12] | Hepatocellular carcinoma | Investigative | |
| Biological Phenomena | Induction-->Blockade of cell cycle in G0/G1 phase | |||
| Gene Regulation | Up-regulation | Expression | TP53 | hsa7157 |
| Up-regulation | Expression | BAX | hsa581 | |
| Down-regulation | Expression | BCL2 | hsa596 | |
| Down-regulation | Expression | BIRC5 | hsa332 | |
| Up-regulation | Expression | ROS1 | hsa6098 | |
| In Vitro Model | QGY-7703 | Papillomavirus-related cervical adenocarcinoma | Homo sapiens (Human) | CVCL_6715 |
| Result | Synergy of Raddeanin A and cisplatin induced therapeutic effect enhancement in human hepatocellular carcinoma | |||
| No. | Title | Href |
|---|---|---|
| 1 | Synergy of Raddeanin A and cisplatin induced therapeutic effect enhancement in human hepatocellular carcinoma. Biochem Biophys Res Commun. 2017 Apr 1;485(2):335-341. doi: 10.1016/j.bbrc.2017.02.079. | Click |
