| Pair Name | Lycopene, Doxorubicin | ||
| Phytochemical Name | Lycopene (PubChem CID: 446925 ) | ||
| Anticancer drug Name | Doxorubicin (PubChem CID: 31703 ) | ||
| Structure of Phytochemical |
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| Structure of Anticancer Drug |
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| Pair Name | Lycopene, Doxorubicin | |||
| Disease Info | [ICD-11: 2C60] | Breast cancer | Investigative | |
| Biological Phenomena | Induction-->Apoptosis | |||
| Gene Regulation | Up-regulation | Cleavage | CASP3 | hsa836 |
| Up-regulation | Cleavage | PARP1 | hsa142 | |
| In Vitro Model | MDA-MB-231 | Breast adenocarcinoma | Homo sapiens (Human) | CVCL_0062 |
| MDA-MB-468 | Breast adenocarcinoma | Homo sapiens (Human) | CVCL_0419 | |
| Result | Our results thus show the therapeutic benefit of red guava extracts as a potential cancer treatment for TNBC in combination with doxorubicin or targeted therapy. | |||
| No. | Title | Href |
|---|---|---|
| 1 | Anti-cancer therapeutic benefit of red guava extracts as a potential therapy in combination with doxorubicin or targeted therapy for triple-negative breast cancer cells. Int J Med Sci. 2020 Apr 6;17(8):1015-1022. doi: 10.7150/ijms.40131. | Click |
