Ginsenoside, Ginsenosides, Panaxosides, Sanchinosides
| Name | Ginsenoside | ||
| PubChem CID | 3086007 | ||
| Molecular Weight | 444.7g/mol | ||
| Synonyms |
Ginsenoside, Ginsenosides, Panaxosides, Sanchinosides |
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| Formula | C₃₀H₅₂O₂ | ||
| SMILES | CC(=CCCC(C)(C1CCC2(C1CCC3C2(CCC4C3(CCC(C4(C)C)O)C)C)C)O)C | ||
| InChI | 1S/C30H52O2/c1-20(2)10-9-16-30(8,32)22-13-18-28(6)21(22)11-12-24-27(5)17-15-25(31)26(3,4)23(27)14-19-29(24,28)7/h10,21-25,31-32H,9,11-19H2,1-8H3/t21?,22-,23-,24+,25-,27-,28+,29+,30?/m0/s1 | ||
| InChIKey | NLHQJXWYMZLQJY-SWIZOJJJSA-N | ||
| CAS Number | 74749-74-9 | ||
| Herb ID | HBIN027694 | ||
| Drug Bank ID | DB14152 | ||
| Toxicity | Organism | Test Type | Route(Dose) |
| rat | LD50 | intraperitoneal(165 mg/kg) | |
| mouse | LD50 | intraperitoneal(254 mg/kg) | |
| rat | LD50 | oral(322 mg/kg) | |
| Structure | 
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Download
2D
MOL
3D
MOL
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| Chineses Pinyin | RenShen | ||
| Use Part | Root | ||
| Habitat | JiLin, LiaoNing, HeiLongJiang | ||
| Flavor | Sweet; Slightly Bitter | ||
| Meridian Tropism | Spleen; Lung; Heart; Kidney | ||
| Species |
>Kingdom: Viridiplantae
-->Phylum: Streptophyta
-->Class: Equisetopsida
-->Order: Apiales
-->Family: Araliaceae
-->Genus: Panax
-->Species: Panax ginseng
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| Pair Name | Ginsenoside, Regorafenib | |||
| Partner Name | Regorafenib | |||
| Disease Info | [ICD-11: 2C12] | Hepatocellular carcinoma | Investigative | |
| Biological Phenomena | Induction-->Apoptosis | |||
| Gene Regulation | Down-regulation | Expression | BIRC5 | hsa332 |
| Up-regulation | Expression | CASP3 | hsa836 | |
| In Vitro Model | Hep-G2 | Hepatoblastoma | Homo sapiens (Human) | CVCL_0027 |
| Result | The findings in this study offered a theoretical insight into clinical use of regorafenib and ginsenoside for treatment of liver cancer. | |||
