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  1. General Info
  2. Effects Info
  3. Reference
Drug Interaction Details
01. General Information
Pair Name Epibrassinolide, Etoposide
Phytochemical Name Epibrassinolide (PubChem CID: 443055 )
Anticancer drug Name Etoposide (PubChem CID: 36462 )
Structure of
Phytochemical
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2D MOL 3D MOL
Structure of
Anticancer Drug
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2D MOL 3D MOL
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Reversing Drug Resistance
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Combination Pair ID: 565
Pair Name Epibrassinolide, Etoposide
Disease Info [ICD-11: 2C25] Lung cancer Investigative
Biological Phenomena Induction-->Apoptosis
Gene Regulation Down-regulation Expression CTNNB1 hsa1499
In Vitro Model NCI-H69 Lung small cell carcinoma Homo sapiens (Human) CVCL_1579
VPA17 Multi-drug resistant small-cell lung cancer Homo sapiens (Human) N.A.
Result Castasterone, a Plant Steroid Hormone, Affects Human Small-Cell Lung Cancer Cells and Reverses Multi-Drug Resistance
03. Reference
No. Title Href
1 Castasterone, a Plant Steroid Hormone, Affects Human Small-Cell Lung Cancer Cells and Reverses Multi-Drug Resistance. Pharmaceuticals (Basel). 2023 Jan 23;16(2):170. doi: 10.3390/ph16020170. Click
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