24-epibrassinolide, 2alpha,3alpha,22alpha,23alpha-tetrahydroxy-24alpha-methyl-B-homo-7-oxa-5alpha-cholestan-6-one, brassinolide, brassinolide, (2alpha,3alpha,5alpha,22S,23S)-isomer, brassinolide, (2alpha,3alpha,5alpha.22R,23R)-isomer
| Name | Epibrassinolide | ||
| PubChem CID | 443055 | ||
| Molecular Weight | 480.7g/mol | ||
| Synonyms |
24-epibrassinolide, 2alpha,3alpha,22alpha,23alpha-tetrahydroxy-24alpha-methyl-B-homo-7-oxa-5alpha-cholestan-6-one, brassinolide, brassinolide, (2alpha,3alpha,5alpha,22S,23S)-isomer, brassinolide, (2alpha,3alpha,5alpha.22R,23R)-isomer |
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| Formula | C₂₈H₄₈O₆ | ||
| SMILES | CC(C)C(C)C(C(C(C)C1CCC2C1(CCC3C2COC(=O)C4C3(CC(C(C4)O)O)C)C)O)O | ||
| InChI | 1S/C28H48O6/c1-14(2)15(3)24(31)25(32)16(4)18-7-8-19-17-13-34-26(33)21-11-22(29)23(30)12-28(21,6)20(17)9-10-27(18,19)5/h14-25,29-32H,7-13H2,1-6H3/t15-,16+,17+,18-,19+,20+,21-,22+,23-,24-,25-,27-,28-/m1/s1 | ||
| InChIKey | IXVMHGVQKLDRKH-QHBHMFGVSA-N | ||
| CAS Number | 78821-43-9 | ||
| ChEMBL ID | CHEMBL563853 | ||
| ChEBI ID | CHEBI:27722 | ||
| KEGG ID | C11049 | ||
| Structure | 
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Download
2D
MOL
3D
MOL
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| Chineses Pinyin | YouCai | ||
| Use Part | Seed | ||
| Species |
>Kingdom: Viridiplantae
-->Phylum: Streptophyta
-->Class: Equisetopsida
-->Order: Brassicales
-->Family: Brassicaceae
-->Genus: Brassica
-->Species: Brassica rapa subsp/ oleifera
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| Pair Name | Epibrassinolide, Etoposide | |||
| Partner Name | Etoposide | |||
| Disease Info | [ICD-11: 2C25] | Lung cancer | Investigative | |
| Biological Phenomena | Induction-->Apoptosis | |||
| Gene Regulation | Down-regulation | Expression | CTNNB1 | hsa1499 |
| In Vitro Model | NCI-H69 | Lung small cell carcinoma | Homo sapiens (Human) | CVCL_1579 |
| VPA17 | Multi-drug resistant small-cell lung cancer | Homo sapiens (Human) | N.A. | |
| Result | Castasterone, a Plant Steroid Hormone, Affects Human Small-Cell Lung Cancer Cells and Reverses Multi-Drug Resistance | |||
