InterPAD - DETAILS

cyclophosphamide, 50-18-0, Cytoxan, Cyclophosphamid, Cyclophosphane, Endoxan, Cytophosphan, Procytox, Sendoxan, Clafen, Cyclophosphan, Cyclostin, Cyclophosphamidum, Cytophosphane, Endoxanal, Neosar, Claphene, Endoxana, Genoxal, Endoxan-Asta, Endoxan R, Zyklophosphamid, Mitoxan, Cyclophosphoramide, Cyklofosfamid, Endoxane, (RS)-Cyclophosphamide, Cyclophosphamide anhydrous, Cyclophosphanum, Enduxan, Semdoxan, Senduxan, (+-)-Cyclophosphamide, Ciclophosphamide, ASTA, Lyophilized Cytoxan, Ciclofosfamida, D,L-Cyclophosphamide, Rcra waste number U058, Asta B 518, (-)-Cyclophosphamide, Cycloblastin, NSC-26271, 2H-1,3,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide, Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester, CB 4564, Cyclophosphamide (anhydrous), NCI-C04900, ASTA B518, SK 20501, NSC 26271, CHEBI:4027, B 518, Occupation, cyclophosphamide exposure, CCRIS 188, N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide, 4-Hydroxy-cyclophosphan-mamophosphatide, HSDB 3047, Anhydrous cyclophosphamide, EINECS 200-015-4, Ciclofosfamide, N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide, UNII-6UXW23996M, BRN 0011744, Cyclophosphamide-d4, AI3-26198, 6UXW23996M, Cyclophosphamide (INN), 1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin, NSC26271, Cytoxan (TN), 2-(Bis(2-chloroethyl)amino)-2H-1,3,2-oxazaphosphorine 2-oxide, N,N-Bis(2-chloroethyl)-N',O-propylenephosphoric acid ester diamide, N,N-Di(2-chloroethyl)-N,O-propylene-phosphoric acid ester diamide, 50-18-0 (anhydrous), 2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide, 2H-1,3,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-,2-oxide, Phosphorodiamidic acid, N,N-bis(2-chloroethyl)-N'-(3-hydroxypropyl)-, intramol. ester, CY, DTXSID5020364, CYCLOPHOSPHAMIDE LYOPHILIZED, CYCLOPHOSPHAMIDE, ANHYDROUS, N,N-Bis(beta-chloroethyl)-N',O-propylenephosphoric acid ester diamide, 2-(Bis(2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazophosphorine 2-oxide, N,N-Bis(beta-chloroethyl)-N',O-trimethylenephosphoric acid ester diamide, Cyklofosfamid [Czech], N,N-bis(2-chloroethyl)-2-oxo-1,3,2$l^{5}-oxazaphosphinan-2-amine, N,N-Bis-(beta-chloraethyl)-N',O-propylen-phosphorsaeure-ester-diamid, Ciclophosphamide [INN], 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide, 2H-1,3,2-Oxazaphosphorine, 2-(bis(2-chloroethyl)amino)tetrahydro-, 2-oxide, Zyklophosphamid [German], NSC-756711, Ciclophosphamide hydrat, Cytoxan (Lyophilized), CYCLOPHOSPHAMIDE [INN], Ciclofosfamida [INN-Spanish], Cyclofosphamide, Cyclophosphamidum [INN-Latin], UNII-8N3DW7272P, CYCLOPHOSPHAMIDE (IARC), CCRIS 7469, CYCLOPHOSPHAMIDE (USP-RS), Cyclophosphamide (anhydrous form), Cyclophosphamide (TN), CYCLOPHOSPHAMIDE (EP MONOGRAPH), CYCLOPHOSPHAMIDE (USP MONOGRAPH), SR-01000075737, NCGC00015209-05, RCRA waste no. U058, Cyclophosphamide [USP:INN], Cycloblastine, Cyclophospham, Cyclostine, Fosfaseron, Syklofosfamid, Carloxan, Cicloxal, Genuxal, Ledoxina, 2-(Bis(2-chloroethyl)amino)-2H-1,2-oxazaphosphorine 2-oxide, 2-[Bis(2-chloroethyl)amino]-2H-1,2-oxazaphosphorine 2-oxide, 2-(Bis(2-chloroethylamino))-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide, (Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,5,6-oxazaphosphorine-1,3,2-oxide-2 hydrate, [Bis(chloro-2-ethyl)amino]-2-tetrahydro-3,5,6-oxazaphosphorine-1,3,2-oxide-2 hydrate, 2-(BIS(2-CHLOROETHYL)AMINO)TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE 2-OXIDE, CYCLO-cell, N,N-Bis(beta-cloraethyl) N'-O-propylenphosphorildiamid monohydratum, 173547-45-0, bis(2-Chloroethyl)phosphamide cyclic propanolamide ester, CB-4564, Spectrum_000858, CHEMBL88, Spectrum2_001146, Spectrum3_000370, Spectrum4_000304, Spectrum5_000795, Lopac-C-0768, Epitope ID:131782, C 0768, N,N-Bis-(beta-chloraethyl)-N',O-propylen-phosphorsaeure-ester-diamid [German], SCHEMBL4346, (.+/-.)-Cyclophosphamide, Lopac0_000238, BSPBio_002099, KBioGR_000888, KBioSS_001338, DivK1c_000246, DTXCID70364, SPBio_001071, CYCLOPHOSPHAMIDE [HSDB], GTPL7154, SCHEMBL4345553, 2-H-1,3,2-Oxazaphosphorinane, SCHEMBL10262910, CMSMOCZEIVJLDB-UHFFFAOYSA-, KBio1_000246, KBio2_001338, KBio2_003906, KBio2_006474, KBio3_001319, CYCLOPHOSPAMIDE MONOHYDRATE, CYCLOPHOSPHAMIDE [WHO-DD], L01AA01, WLN: T6MPOTJ BO BN2G2G, NINDS_000246, 2-(bis(2-chloroethyl)amino)-1,3,2-oxazaphosphinane 2-oxide, HMS2090A12, HMS3260P17, HMS3715J05, Pharmakon1600-01500213, AMY33449, BCP02139, Tox21_500238, BDBM50237604, N,N-bis(2-chloroethyl)-2-oxo-1,3,2lambda5-oxazaphosphinan-2-amine, NSC273033, NSC273034, NSC756711, STK177249, AKOS005410738, tetrahydro-N,N-bis(2-chloroethyl)-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide, CS-1425, CYCLOPHOSPHAMIDE ANHYDROUS [MI], DB00531, LP00238, NSC-273033, NSC-273034, SDCCGSBI-0050226.P004, IDI1_000246, N,3,2-oxazaphosphorin-2-amine-2-oxide, N,O-propylen-phosphorsaeure-ester-diamid, NCGC00015209-01, NCGC00015209-02, NCGC00015209-03, NCGC00015209-04, NCGC00015209-06, NCGC00015209-07, NCGC00015209-08, NCGC00015209-09, NCGC00015209-12, NCGC00015209-28, NCGC00091741-02, NCGC00091741-03, NCGC00260923-01, AS-73255, BP-25411, HY-17420, NCI60_002097, N,O-propylenephosphoric acid ester diamide, SBI-0050226.P003, DB-082057, N,O-propylene-phosphoric acid ester diamide, WR-138719, C2236, EU-0100238, FT-0624276, FT-0665387, N,O-trimethylenephosphoric acid ester diamide, NS00000339, EN300-74526, C07888, D07760, AB00053446-09, AB00053446-11, AB00053446-12, AB00053446_13, AB00053446_14, AB00053446_15, Q408524, W-60377, N,O-propylenephosphoric acid ester amide monohydrate, SR-01000075737-1, SR-01000075737-6, W-105248, BRD-A09722536-002-02-4, Z276509078, 2-(bis(2-chloroethyl)amino)-1,3,2-oxazaphosphinane2-oxide, Bis(2-chloroethyl)phosphoramide-cyclic propanolamide ester, 2-[bis(2-chloroethyl)amino]-1,3,2??-oxazaphosphinan-2-one, 1-BIS(2-CHLOROETHYL)AMINO-1-OXO-2-AZA-5-OXAPHOSPHORIDINE, 2-[bis(2-chloroethyl)amino]-1,3,2$l^{5}-oxazaphosphinan-2-one, 2-[bis(2-chloroethyl)amino]-1,3,2lambda5-oxazaphosphinan-2-one, N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide #, 2-[Bis(2-chloroethyl)amino]tetrahydro-1,3,2-oxazaphosphorin-2-oxide, 2H-1,2-Oxazaphosphorine, 2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide, 2H-1,3,2-Oxazaphosphorine, 2-(bis(2-chloroethyl)amino)tetrahydro-,2-oxide, N,N-Bis(.beta.-chloroethyl)-N',O-trimethylenephosphoric acid ester diamide, N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine-2-oxide, N,N-Bis-(.beta.-chloraethyl)-N',O-propylen-phosphorsaeure-ester-diamid, N,N-DI(2-CHLOROETHYL)-N,O-PROPYLENE PHOSPHORIC ACID ESTER DIAMIDE, (+/-)-2-(BIS(2-CHLOROETHYL)AMINO)TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE 2-OXIDE, 2-(DI(2-CHLOROETHYLAMINO))-1-OXA-3-AZA-2-PHOSPHACYCLOHEXANE 2-OXIDE, 2-Bis(2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide, 2H-1,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide, 2H-1,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide, (+)-, 2H-1,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide, (-)-, 2H-1,2-Oxazaphosphorine, 2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide, monohydrate, 2H-1,3,2-oxazaphosphorin-2-amine, N,N-is(2-chloroethyl)tetrahydro-,2-oxide, N,N-bis(2-chloroethyl)-2-oxo-1-oxa-3-aza-2$l^{5}-phosphacyclohexan-2-amine, N,N-BIS(2-CHLOROETHYL)-N'-(3-HYDROXYPROPYL)PHOSPHORODIAMIDIC ACID INTRAMOL., N,N-BIS(BETA-CHLOROETHYL)N',O-TRIMETHYLENEPHOSPHORIC ACID ESTER DIAMIDE, Phosphorodiamidic acid,N-bis(2-chloroethyl)-N'-(3-hydroxypropyl)-, intramol. ester, InChI=1/C7H15Cl2N2O2P/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14/h1-7H2,(H,10,12)

Name	Cyclophosphamide
PubChem CID	2907
Molecular Weight	261.08g/mol
Synonyms	cyclophosphamide, 50-18-0, Cytoxan, Cyclophosphamid, Cyclophosphane, Endoxan, Cytophosphan, Procytox, Sendoxan, Clafen, Cyclophosphan, Cyclostin, Cyclophosphamidum, Cytophosphane, Endoxanal, Neosar, Claphene, Endoxana, Genoxal, Endoxan-Asta, Endoxan R, Zyklophosphamid, Mitoxan, Cyclophosphoramide, Cyklofosfamid, Endoxane, (RS)-Cyclophosphamide, Cyclophosphamide anhydrous, Cyclophosphanum, Enduxan, Semdoxan, Senduxan, (+-)-Cyclophosphamide, Ciclophosphamide, ASTA, Lyophilized Cytoxan, Ciclofosfamida, D,L-Cyclophosphamide, Rcra waste number U058, Asta B 518, (-)-Cyclophosphamide, Cycloblastin, NSC-26271, 2H-1,3,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide, Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester, CB 4564, Cyclophosphamide (anhydrous), NCI-C04900, ASTA B518, SK 20501, NSC 26271, CHEBI:4027, B 518, Occupation, cyclophosphamide exposure, CCRIS 188, N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide, 4-Hydroxy-cyclophosphan-mamophosphatide, HSDB 3047, Anhydrous cyclophosphamide, EINECS 200-015-4, Ciclofosfamide, N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide, UNII-6UXW23996M, BRN 0011744, Cyclophosphamide-d4, AI3-26198, 6UXW23996M, Cyclophosphamide (INN), 1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin, NSC26271, Cytoxan (TN), 2-(Bis(2-chloroethyl)amino)-2H-1,3,2-oxazaphosphorine 2-oxide, N,N-Bis(2-chloroethyl)-N',O-propylenephosphoric acid ester diamide, N,N-Di(2-chloroethyl)-N,O-propylene-phosphoric acid ester diamide, 50-18-0 (anhydrous), 2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide, 2H-1,3,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-,2-oxide, Phosphorodiamidic acid, N,N-bis(2-chloroethyl)-N'-(3-hydroxypropyl)-, intramol. ester, CY, DTXSID5020364, CYCLOPHOSPHAMIDE LYOPHILIZED, CYCLOPHOSPHAMIDE, ANHYDROUS, N,N-Bis(beta-chloroethyl)-N',O-propylenephosphoric acid ester diamide, 2-(Bis(2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazophosphorine 2-oxide, N,N-Bis(beta-chloroethyl)-N',O-trimethylenephosphoric acid ester diamide, Cyklofosfamid [Czech], N,N-bis(2-chloroethyl)-2-oxo-1,3,2$l^{5}-oxazaphosphinan-2-amine, N,N-Bis-(beta-chloraethyl)-N',O-propylen-phosphorsaeure-ester-diamid, Ciclophosphamide [INN], 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide, 2H-1,3,2-Oxazaphosphorine, 2-(bis(2-chloroethyl)amino)tetrahydro-, 2-oxide, Zyklophosphamid [German], NSC-756711, Ciclophosphamide hydrat, Cytoxan (Lyophilized), CYCLOPHOSPHAMIDE [INN], Ciclofosfamida [INN-Spanish], Cyclofosphamide, Cyclophosphamidum [INN-Latin], UNII-8N3DW7272P, CYCLOPHOSPHAMIDE (IARC), CCRIS 7469, CYCLOPHOSPHAMIDE (USP-RS), Cyclophosphamide (anhydrous form), Cyclophosphamide (TN), CYCLOPHOSPHAMIDE (EP MONOGRAPH), CYCLOPHOSPHAMIDE (USP MONOGRAPH), SR-01000075737, NCGC00015209-05, RCRA waste no. U058, Cyclophosphamide [USP:INN], Cycloblastine, Cyclophospham, Cyclostine, Fosfaseron, Syklofosfamid, Carloxan, Cicloxal, Genuxal, Ledoxina, 2-(Bis(2-chloroethyl)amino)-2H-1,2-oxazaphosphorine 2-oxide, 2-[Bis(2-chloroethyl)amino]-2H-1,2-oxazaphosphorine 2-oxide, 2-(Bis(2-chloroethylamino))-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide, (Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,5,6-oxazaphosphorine-1,3,2-oxide-2 hydrate, [Bis(chloro-2-ethyl)amino]-2-tetrahydro-3,5,6-oxazaphosphorine-1,3,2-oxide-2 hydrate, 2-(BIS(2-CHLOROETHYL)AMINO)TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE 2-OXIDE, CYCLO-cell, N,N-Bis(beta-cloraethyl) N'-O-propylenphosphorildiamid monohydratum, 173547-45-0, bis(2-Chloroethyl)phosphamide cyclic propanolamide ester, CB-4564, Spectrum_000858, CHEMBL88, Spectrum2_001146, Spectrum3_000370, Spectrum4_000304, Spectrum5_000795, Lopac-C-0768, Epitope ID:131782, C 0768, N,N-Bis-(beta-chloraethyl)-N',O-propylen-phosphorsaeure-ester-diamid [German], SCHEMBL4346, (.+/-.)-Cyclophosphamide, Lopac0_000238, BSPBio_002099, KBioGR_000888, KBioSS_001338, DivK1c_000246, DTXCID70364, SPBio_001071, CYCLOPHOSPHAMIDE [HSDB], GTPL7154, SCHEMBL4345553, 2-H-1,3,2-Oxazaphosphorinane, SCHEMBL10262910, CMSMOCZEIVJLDB-UHFFFAOYSA-, KBio1_000246, KBio2_001338, KBio2_003906, KBio2_006474, KBio3_001319, CYCLOPHOSPAMIDE MONOHYDRATE, CYCLOPHOSPHAMIDE [WHO-DD], L01AA01, WLN: T6MPOTJ BO BN2G2G, NINDS_000246, 2-(bis(2-chloroethyl)amino)-1,3,2-oxazaphosphinane 2-oxide, HMS2090A12, HMS3260P17, HMS3715J05, Pharmakon1600-01500213, AMY33449, BCP02139, Tox21_500238, BDBM50237604, N,N-bis(2-chloroethyl)-2-oxo-1,3,2lambda5-oxazaphosphinan-2-amine, NSC273033, NSC273034, NSC756711, STK177249, AKOS005410738, tetrahydro-N,N-bis(2-chloroethyl)-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide, CS-1425, CYCLOPHOSPHAMIDE ANHYDROUS [MI], DB00531, LP00238, NSC-273033, NSC-273034, SDCCGSBI-0050226.P004, IDI1_000246, N,3,2-oxazaphosphorin-2-amine-2-oxide, N,O-propylen-phosphorsaeure-ester-diamid, NCGC00015209-01, NCGC00015209-02, NCGC00015209-03, NCGC00015209-04, NCGC00015209-06, NCGC00015209-07, NCGC00015209-08, NCGC00015209-09, NCGC00015209-12, NCGC00015209-28, NCGC00091741-02, NCGC00091741-03, NCGC00260923-01, AS-73255, BP-25411, HY-17420, NCI60_002097, N,O-propylenephosphoric acid ester diamide, SBI-0050226.P003, DB-082057, N,O-propylene-phosphoric acid ester diamide, WR-138719, C2236, EU-0100238, FT-0624276, FT-0665387, N,O-trimethylenephosphoric acid ester diamide, NS00000339, EN300-74526, C07888, D07760, AB00053446-09, AB00053446-11, AB00053446-12, AB00053446_13, AB00053446_14, AB00053446_15, Q408524, W-60377, N,O-propylenephosphoric acid ester amide monohydrate, SR-01000075737-1, SR-01000075737-6, W-105248, BRD-A09722536-002-02-4, Z276509078, 2-(bis(2-chloroethyl)amino)-1,3,2-oxazaphosphinane2-oxide, Bis(2-chloroethyl)phosphoramide-cyclic propanolamide ester, 2-[bis(2-chloroethyl)amino]-1,3,2??-oxazaphosphinan-2-one, 1-BIS(2-CHLOROETHYL)AMINO-1-OXO-2-AZA-5-OXAPHOSPHORIDINE, 2-[bis(2-chloroethyl)amino]-1,3,2$l^{5}-oxazaphosphinan-2-one, 2-[bis(2-chloroethyl)amino]-1,3,2lambda5-oxazaphosphinan-2-one, N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide #, 2-[Bis(2-chloroethyl)amino]tetrahydro-1,3,2-oxazaphosphorin-2-oxide, 2H-1,2-Oxazaphosphorine, 2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide, 2H-1,3,2-Oxazaphosphorine, 2-(bis(2-chloroethyl)amino)tetrahydro-,2-oxide, N,N-Bis(.beta.-chloroethyl)-N',O-trimethylenephosphoric acid ester diamide, N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine-2-oxide, N,N-Bis-(.beta.-chloraethyl)-N',O-propylen-phosphorsaeure-ester-diamid, N,N-DI(2-CHLOROETHYL)-N,O-PROPYLENE PHOSPHORIC ACID ESTER DIAMIDE, (+/-)-2-(BIS(2-CHLOROETHYL)AMINO)TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE 2-OXIDE, 2-(DI(2-CHLOROETHYLAMINO))-1-OXA-3-AZA-2-PHOSPHACYCLOHEXANE 2-OXIDE, 2-Bis(2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide, 2H-1,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide, 2H-1,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide, (+)-, 2H-1,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide, (-)-, 2H-1,2-Oxazaphosphorine, 2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide, monohydrate, 2H-1,3,2-oxazaphosphorin-2-amine, N,N-is(2-chloroethyl)tetrahydro-,2-oxide, N,N-bis(2-chloroethyl)-2-oxo-1-oxa-3-aza-2$l^{5}-phosphacyclohexan-2-amine, N,N-BIS(2-CHLOROETHYL)-N'-(3-HYDROXYPROPYL)PHOSPHORODIAMIDIC ACID INTRAMOL., N,N-BIS(BETA-CHLOROETHYL)N',O-TRIMETHYLENEPHOSPHORIC ACID ESTER DIAMIDE, Phosphorodiamidic acid,N-bis(2-chloroethyl)-N'-(3-hydroxypropyl)-, intramol. ester, InChI=1/C7H15Cl2N2O2P/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14/h1-7H2,(H,10,12)
Drug Type	Small molecule
Formula	C₇H₁₅Cl₂N₂O₂P
SMILES	C1CNP(=O)(OC1)N(CCCl)CCCl
InChI	1S/C7H15Cl2N2O2P/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14/h1-7H2,(H,10,12)
InChIKey	CMSMOCZEIVJLDB-UHFFFAOYSA-N
CAS Number	50-18-0
ChEMBL ID	CHEMBL88
ChEBI ID	CHEBI:4027
TTD ID	D0CT9C
Drug Bank ID	DB00531
KEGG ID	C07888
Toxicity	Organism	Test Type	Route(Dose)
	rat	LD50	intraperitoneal(165 mg/kg)
	mouse	LD50	intraperitoneal(254 mg/kg)
	rat	LD50	oral(322 mg/kg)
Structure			Download 2D MOL 3D MOL

Pair Name	Thymoquinone, Cyclophosphamide
Partner Name	Thymoquinone
Disease Info	[ICD-11: 2C60]	Breast cancer		Investigative
Biological Phenomena	Induction-->Blockade of cell cycle in Sub-G1 phase
Gene Regulation	Down-regulation	Phosphorylation	AKT1	hsa207
	Down-regulation	Expression	CCND1	hsa595
	Up-regulation	Expression	PTEN	hsa5728
In Vitro Model	SK-BR-3	Breast adenocarcinoma	Homo sapiens (Human)	CVCL_0033
In Vitro Model	MDA-MB-231	Breast adenocarcinoma	Homo sapiens (Human)	CVCL_0062
Result	The current findings suggested that TQ can alter the cell cycle progression and induce cell death independent of FASN mediated signaling. In terms of clinical perspective, the present study clearly showed that TQ can broadly augment the effect of cyclo in breast cancer cases irrespective of Her-2+ or Her-.

Pair Name	Quercetin, Cyclophosphamide
Partner Name	Quercetin
Disease Info	[ICD-11: 2C60]	Breast cancer		Investigative
Biological Phenomena	Induction-->Immunomodulatory
In Vitro Model	4T1	Malignant neoplasms of the mouse mammary gland	Mus musculus (Mouse)	CVCL_0125
In Vivo Model	4T1 cells (5×10³) in 100 µL of phosphate-buffered saline (PBS) were injected into one axillary mammary fat pad per mouse of 5–6-week-old female immunocompetent BALB/c mice.
Result	Complementarity between Microbiome and Immunity May Account for the Potentiating Effect of Quercetin on the Antitumor Action of Cyclophosphamide in a Triple-Negative Breast Cancer Model

Pair Name	Pixinol, Cyclophosphamide
Partner Name	Pixinol
Disease Info	[ICD-11: 2C12]	Hepatocellular carcinoma		Investigative
In Vitro Model	Hep-G2	Hepatoblastoma	Homo sapiens (Human)	CVCL_0027
Result	These results suggest that compound 2e is a promising agent for anti-hepato-carcinoma, and that it also could be used in combination with CTX to increase efficiency and to reduce toxicity.

Pair Name	Isoliquiritigenin, Cyclophosphamide
Partner Name	Isoliquiritigenin
Disease Info	[ICD-11: 2C77]	Cervical cancer		Investigative
Biological Phenomena	Induction-->DNA damage
In Vitro Model	U14	Cervical carcinoma	Mus musculus (Mouse)	CVCL_9U56
In Vivo Model	KM mice were implanted subcutaneously with 0.2 mL (1×10⁷ mL in sodium chloride) U14 cells.
Result	Isoliquiritigen enhances the antitumour activity and decreases the genotoxic effect of cyclophosphamide

No.	Title	Href
1	Synthesis and Anti-Hepatocarcinoma Effect of Amino Acid Derivatives of Pyxinol and Ocotillol. Molecules. 2021 Feb 3;26(4):780. doi: 10.3390/molecules26040780.	`Click`
2	Isoliquiritigen enhances the antitumour activity and decreases the genotoxic effect of cyclophosphamide. Molecules. 2013 Jul 24;18(8):8786-98. doi: 10.3390/molecules18088786.	`Click`
3	Thymoquinone Augments Cyclophosphamide-Mediated Inhibition of Cell Proliferation in Breast Cancer Cells. Asian Pac J Cancer Prev. 2019 Apr 29;20(4):1153-1160. doi: 10.31557/APJCP.2019.20.4.1153.	`Click`
4	Complementarity between Microbiome and Immunity May Account for the Potentiating Effect of Quercetin on the Antitumor Action of Cyclophosphamide in a Triple-Negative Breast Cancer Model. Pharmaceuticals (Basel). 2023 Oct 6;16(10):1422. doi: 10.3390/ph16101422.	`Click`