| Pair Name | Thymoquinone, Simvastatin | ||
| Phytochemical Name | Thymoquinone (PubChem CID: 10281 ) | ||
| Anticancer drug Name | Simvastatin (PubChem CID: 54454 ) | ||
| Structure of Phytochemical |
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| Structure of Anticancer Drug |
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| Pair Name | Thymoquinone, Simvastatin | |||
| Disease Info | [ICD-11: 2C60] | Breast cancer | Investigative | |
| Biological Phenomena | Induction-->Blockade of cell cycle in G2/M phase | |||
| In Vitro Model | MCF-7 | Invasive breast carcinoma of no special type | Homo sapiens (Human) | CVCL_0031 |
| MDA-MB-231 | Breast adenocarcinoma | Homo sapiens (Human) | CVCL_0062 | |
| Result | It was concluded that the combined effect of simvastatin and thymoquinone stimulates apoptosis in breast cancer cells. | |||
| No. | Title | Href |
|---|---|---|
| 1 | Evaluation of Enhanced Cytotoxicity Effect of Repurposed Drug Simvastatin/ Thymoquinone Combination against Breast Cancer Cell Line. Cardiovasc Hematol Agents Med Chem. 2023 Oct 27. doi: 10.2174/0118715257259037231012182741. | Click |
