
| Name | Tumor necrosis factor receptor type 1-associated DEATH domain protein | ||
| UniProt ID | TRADD_HUMAN | ||
| Gene Name | TRADD | ||
| Gene ID | 8717 | ||
| Synonyms |
TRADD, Hs.89862
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| Sequence |
MAAGQNGHEEWVGSAYLFVESSLDKVVLSDAYAHPQQKVAVYRALQAALAESGGSPDVLQ
MLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHSVPLQLELRA GAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPL QPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRG CRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAED LLGLTDPNGGLA |
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| Pathway Map | MAP LINK | ||
| T.C. Number | 3.D.3.5.2 | ||
| KEGG ID | hsa8717 | ||
| Pfam | PF00531; PF09034; PF16739; PF20694 | ||
| Pair Name | Naringenin, AMG-951 | |||
| Phytochemical | Naringenin | |||
| Drug | AMG-951 | |||
| Disease Info | [ICD-11: 2F7Z] | Glioma | Investigative | |
| Regulate Info | Up-regulation | Tumor necrosis factor receptor type 1-associated DEATH domain protein | Expression | |
| Result | The present study provides a novel therapeutic strategy for glioma by potentiating APO2L-induced apoptosis via the combination with NG in glioma tumor cells. | |||