Name | Tumor necrosis factor receptor type 1-associated DEATH domain protein | ||
UniProt ID | TRADD_HUMAN | ||
Gene Name | TRADD | ||
Gene ID | 8717 | ||
Synonyms |
TRADD, Hs.89862
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Sequence |
MAAGQNGHEEWVGSAYLFVESSLDKVVLSDAYAHPQQKVAVYRALQAALAESGGSPDVLQ
MLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHSVPLQLELRA GAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPL QPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRG CRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAED LLGLTDPNGGLA |
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Pathway Map | MAP LINK | ||
T.C. Number | 3.D.3.5.2 | ||
KEGG ID | hsa8717 | ||
Pfam | PF00531; PF09034; PF16739; PF20694 |
Pair Name | Naringenin, AMG-951 | |||
Phytochemical | Naringenin | |||
Drug | AMG-951 | |||
Disease Info | [ICD-11: 2F7Z] | Glioma | Investigative | |
Regulate Info | Up-regulation | Tumor necrosis factor receptor type 1-associated DEATH domain protein | Expression | |
Result | The present study provides a novel therapeutic strategy for glioma by potentiating APO2L-induced apoptosis via the combination with NG in glioma tumor cells. |