InterPAD - DETAILS

293754-55-9, T0901317, T 0901317, TO-901317, T-0901317, N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide, Benzenesulfonamide, N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-, N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE, N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-(2,2,2-trifluoroethyl)benzenesulfonamide, TO901317, CHEMBL62136, T-1317, ML125, A07663A39I, N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzenesulfonamide, N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxy-propan-2-yl)phenyl)-N-(2,2,2-trifluoroethyl)benzenesulfonamide, [3H]T0901317, SR-05000000453, C17H12F9NO3S, UNII-A07663A39I, 1pqc, BENZENESULFONAMIDE, N-(2,2,2-TRIFLUOROETHYL)-N-(4-(2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL)PHENYL)-, N-(2,2,2-TRIFLUOROETHYL)-N-(4-(2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL)PHENYL)BENZENESULFONAMIDE, 2o9i, 4nb6, TO 901317, T 1317, MLS002554297, SCHEMBL457231, GTPL2755, DTXSID6040618, BDBM19993, GLXC-02675, HMS3268P10, HMS3413I08, HMS3649G14, HMS3652B22, HMS3677I08, HMS3886B11, BCP03658, EX-A1278, MFCD03412028, s7076, AKOS017345034, CCG-269558, CS-5951, DB07080, SB19595, NCGC00159555-01, NCGC00159555-02, NCGC00159555-03, NCGC00159555-06, AC-32646, Benzenesulfonamide,N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-, HY-10626, SMR001456586, BCP0726000164, NS00068651, SW203816-2, J1.503.100J, C74506, A876482, J-017492, SR-05000000453-1, SR-05000000453-2, SR-05000000453-5, T-901317, BRD-K23383398-001-01-6, Q27088909, T0901317, >=98%, Benzenesulfonamide,?N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-, N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide, N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2, 2-trifluoroethyl)benzenesulfonamide

Name	T0901317
PubChem CID	447912
Molecular Weight	481.3g/mol
Synonyms	293754-55-9, T0901317, T 0901317, TO-901317, T-0901317, N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide, Benzenesulfonamide, N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-, N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE, N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-(2,2,2-trifluoroethyl)benzenesulfonamide, TO901317, CHEMBL62136, T-1317, ML125, A07663A39I, N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzenesulfonamide, N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxy-propan-2-yl)phenyl)-N-(2,2,2-trifluoroethyl)benzenesulfonamide, [3H]T0901317, SR-05000000453, C17H12F9NO3S, UNII-A07663A39I, 1pqc, BENZENESULFONAMIDE, N-(2,2,2-TRIFLUOROETHYL)-N-(4-(2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL)PHENYL)-, N-(2,2,2-TRIFLUOROETHYL)-N-(4-(2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL)PHENYL)BENZENESULFONAMIDE, 2o9i, 4nb6, TO 901317, T 1317, MLS002554297, SCHEMBL457231, GTPL2755, DTXSID6040618, BDBM19993, GLXC-02675, HMS3268P10, HMS3413I08, HMS3649G14, HMS3652B22, HMS3677I08, HMS3886B11, BCP03658, EX-A1278, MFCD03412028, s7076, AKOS017345034, CCG-269558, CS-5951, DB07080, SB19595, NCGC00159555-01, NCGC00159555-02, NCGC00159555-03, NCGC00159555-06, AC-32646, Benzenesulfonamide,N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-, HY-10626, SMR001456586, BCP0726000164, NS00068651, SW203816-2, J1.503.100J, C74506, A876482, J-017492, SR-05000000453-1, SR-05000000453-2, SR-05000000453-5, T-901317, BRD-K23383398-001-01-6, Q27088909, T0901317, >=98%, Benzenesulfonamide,?N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-, N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide, N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2, 2-trifluoroethyl)benzenesulfonamide
Drug Type	Small molecule
Formula	C₁₇H₁₂F₉NO₃S
SMILES	C1=CC=C(C=C1)S(=O)(=O)N(CC(F)(F)F)C2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O
InChI	1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2
InChIKey	SGIWFELWJPNFDH-UHFFFAOYSA-N
CAS Number	293754-55-9
ChEMBL ID	CHEMBL62136
TTD ID	D0B5FC
Drug Bank ID	DB07080
KEGG ID	C15630
Toxicity	Organism	Test Type	Route(Dose)
Structure			Download 2D MOL 3D MOL

Pair Name	Lycopene, T0901317
Partner Name	Lycopene
Disease Info	[ICD-11: 2C25]	Lung cancer		Investigative
Biological Phenomena	Inhibition-->Cell proliferation
Gene Regulation	Up-regulation	Expression	ABCA1	hsa19
	Up-regulation	Expression	NR1H3	hsa10062
	Up-regulation	Expression	PPARG	hsa5468
In Vitro Model	DU145	Prostate carcinoma	Homo sapiens (Human)	CVCL_0105
In Vitro Model	PC-3	Prostate carcinoma	Homo sapiens (Human)	CVCL_0035
Result	These results demonstrate that lycopene can inhibit DU145 cell proliferation via PPARγ-LXRα-ABCA1 pathway and that lycopene and T0901317 exhibit synergistic effects.