| Name | Oxysterols receptor LXR-alpha | ||
| UniProt ID | NR1H3_HUMAN | ||
| Gene Name | NR1H3 | ||
| Gene ID | 10062 | ||
| Synonyms |
NR1H3, LXR-a, LXRA, RLD-1
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| Sequence |
MSLWLGAPVPDIPPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHSAGGTAGVGLEA
AEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKG FFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLK RQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPM APDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLL ETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLI AISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSV HSEQVFALRLQDKKLPPLLSEIWDVHE |
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| Pathway Map | MAP LINK | ||
| T.C. Number | 9.B.208.1.7 | ||
| KEGG ID | hsa10062 | ||
| TTD ID | T52297 | ||
| Pfam | PF00104; PF00105 | ||
| Pair Name | Lycopene, T0901317 | |||
| Phytochemical | Lycopene | |||
| Drug | T0901317 | |||
| Disease Info | [ICD-11: 2C25] | Lung cancer | Investigative | |
| Regulate Info | Up-regulation | Oxysterols receptor LXR-alpha | Expression | |
| Result | These results demonstrate that lycopene can inhibit DU145 cell proliferation via PPARγ-LXRα-ABCA1 pathway and that lycopene and T0901317 exhibit synergistic effects. | |||
