| Pair Name | Sulforaphane, Lapatinib | ||
| Phytochemical Name | Sulforaphane (PubChem CID: 5350 ) | ||
| Anticancer drug Name | Lapatinib (PubChem CID: 208908 ) | ||
| Structure of Phytochemical |
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| Structure of Anticancer Drug |
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| Pair Name | Sulforaphane, Lapatinib | |||
| Disease Info | [ICD-11: 2B72.Z] | Gastric cancer | Investigative | |
| Biological Phenomena | Induction-->Blockade of cell cycle in G0/G1 phase | |||
| Gene Regulation | Down-regulation | Phosphorylation | ERBB2 | hsa2064 |
| Down-regulation | Phosphorylation | AKT1 | hsa207 | |
| Down-regulation | Phosphorylation | MAPK1 | hsa5594 | |
| In Vitro Model | SGC-7901 | Human papillomavirus-related cervical adenocarcinoma | Homo sapiens (Human) | CVCL_0520 |
| Result | Therapeutic Mechanism of Lapatinib Combined with Sulforaphane on Gastric Cancer | |||
| No. | Title | Href |
|---|---|---|
| 1 | Therapeutic Mechanism of Lapatinib Combined with Sulforaphane on Gastric Cancer. Evid Based Complement Alternat Med. 2021 Sep 18;2021:9933274. doi: 10.1155/2021/9933274. | Click |
