| Name | Se-Methylselenocysteine | ||
| PubChem CID | 147004 | ||
| Molecular Weight | 182.09g/mol | ||
| Synonyms |
L-methyl-selenocysteine, methyl selenocysteine, methylselenocysteine, Se-methyl-selenocysteine, Se-methylselenocysteine, selenohomocysteine, selenomethylselenocysteine, selenomethylselenocysteine, (D,L)-isomer, selenomethylselenocysteine, (L)-isomer, selenomethylselenocysteine, (L)-isomer, 75Se-labeled, SeMCys |
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| Formula | C₄H₉NO₂Se | ||
| SMILES | C[Se]CC(C(=O)O)N | ||
| InChI | 1S/C4H9NO2Se/c1-8-2-3(5)4(6)7/h3H,2,5H2,1H3,(H,6,7)/t3-/m0/s1 | ||
| InChIKey | XDSSPSLGNGIIHP-VKHMYHEASA-N | ||
| CAS Number | 26046-90-2 | ||
| ChEMBL ID | CHEMBL62382 | ||
| ChEBI ID | CHEBI:27812 | ||
| Drug Bank ID | DB12697 | ||
| KEGG ID | C05689 | ||
| Structure | 
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Download
2D
MOL
3D
MOL
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| Chineses Pinyin | DaSuan | ||
| Use Part | Bulb | ||
| Habitat | China | ||
| Flavor | Pungent | ||
| Meridian Tropism | Spleen; Stomach; Lung | ||
| Species |
>Kingdom: Viridiplantae
-->Phylum: Streptophyta
-->Class: Equisetopsida
-->Order: Asparagales
-->Family: Amaryllidaceae
-->Genus: Allium
-->Species: Allium sativum
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| Pair Name | Se-Methylselenocysteine, Gemcitabine | |||
| Partner Name | Gemcitabine | |||
| Disease Info | [ICD-11: 2C25] | Lung cancer | Investigative | |
| Biological Phenomena | Induction-->Apoptosis | |||
| Gene Regulation | Up-regulation | Expression | CASP3 | hsa836 |
| Up-regulation | Cleavage | PARP1 | hsa142 | |
| In Vitro Model | A-549 | Lung adenocarcinoma | Homo sapiens (Human) | CVCL_0023 |
| Result | Antitumor study in Ehrlich solid tumor model showed the efficacy of MSC combination with GEM for the enhanced antitumor activity. The proposed combination demonstrated the potential for further translational studies. | |||
