| Name | Solute carrier family 22 member 1 | ||
| UniProt ID | S22A1_HUMAN | ||
| Gene Name | SLC22A1 | ||
| Gene ID | 6580 | ||
| Synonyms |
SLC22A1, HOCT1, OCT1, oct1_cds
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| Sequence |
MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQ
RCGWSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGP CQDGWVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMY QMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIK IMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFTDSVL YQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVM IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIIT PFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGRKAKPKEN TIYLKVQTSEPSGT |
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| Pathway Map | MAP LINK | ||
| T.C. Number | 2.A.1.19.29 | ||
| KEGG ID | hsa6580 | ||
| Pfam | PF00083; PF07690 | ||
| Pair Name | Thymoquinone, Imatinib | |||
| Phytochemical | Thymoquinone | |||
| Drug | Imatinib | |||
| Disease Info | [ICD-11: 2B90.Z] | Colon cancer | Investigative | |
| Regulate Info | Down-regulation | Solute carrier family 22 member 1 | Expression | |
| Result | TQ potentiates IM efficacy on HCT116 cells via uptake/efflux genes modulation | |||
