| Name | Nicotinamide N-methyltransferase | ||
| UniProt ID | NNMT_HUMAN | ||
| Gene Name | NNMT | ||
| Gene ID | 4837 | ||
| Synonyms |
NNMT
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| Sequence |
MESGFTSKDTYLSHFNPRDYLEKYYKFGSRHSAESQILKHLLKNLFKIFCLDGVKGDLLI
DIGSGPTIYQLLSACESFKEIVVTDYSDQNLQELEKWLKKEPEAFDWSPVVTYVCDLEGN RVKGPEKEEKLRQAVKQVLKCDVTQSQPLGAVPLPPADCVLSTLCLDAACPDLPTYCRAL RNLGSLLKPGGFLVIMDALKSSYYMIGEQKFSSLPLGREAVEAAVKEAGYTIEWFEVISQ SYSSTMANNEGLFSLVARKLSRPL |
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| Pathway Map | MAP LINK | ||
| KEGG ID | hsa4837 | ||
| Pfam | PF01234; PF08241; PF08242; PF13489 | ||
| Pair Name | Vanillin, Fluorouracil | |||
| Phytochemical | Vanillin | |||
| Drug | Fluorouracil | |||
| Disease Info | [ICD-11: 2B91.Z] | Colorectal cancer | Investigative | |
| Regulate Info | Down-regulation | Nicotinamide N-methyltransferase | Expression | |
| Result | Vanillin is deemed to be a promising anticancer candidate by inhibiting NNMT and may attenuate NNMT‑induced resistance to 5‑Fu in human CRC therapy with few side effects. | |||
