| Name | Mitochondrial fission factor | ||
| UniProt ID | MFF_HUMAN | ||
| Gene Name | MFF | ||
| Gene ID | 56947 | ||
| Synonyms |
MFF, C2orf33, EMPF2, GL004
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| Sequence |
MSKGTSSDTSLGRVSRAAFPSPTAAEMAEISRIQYEMEYTEGISQRMRVPEKLKVAPPNA
DLEQGFQEGVPNASVIMQVPERIVVAGNNEDVSFSRPADLDLIQSTPFKPLALKTPPRVL TLSERPLDFLDLERPPTTPQNEEIRAVGRLKRERSMSENAVRQNGQLVRNDSLWHRSDSA PRNKISRFQAPISAPEYTVTPSPQQARVCPPHMLPEDGANLSSARGILSLIQSSTRRAYQ QILDVLDENRRPVLRGGSAAATSNPHHDNVRYGISNIDTTIEGTSDDLTVVDAASLRRQI IKLNRRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFRR |
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| Pathway Map | MAP LINK | ||
| T.C. Number | 8.A.166.1.1; 8.A.166.1.2; 8.A.166.1.5; 8.A.166.1.8; 8.A.166.1.9 | ||
| KEGG ID | hsa56947 | ||
| Pfam | PF05644; PF12540 | ||
| Pair Name | Cepharanthine, Epirubicin | |||
| Phytochemical | Cepharanthine | |||
| Drug | Epirubicin | |||
| Disease Info | [ICD-11: 2C60] | Breast cancer | Investigative | |
| Regulate Info | Up-regulation | Mitochondrial fission factor | Expression | |
| Result | Cepharanthine sensitizes human triple negative breast cancer cells to chemotherapeutic agent epirubicin via inducing cofilin oxidation-mediated mitochondrial fission and apoptosis | |||
