| Name | Keratin type II cytoskeletal 8 | ||
| UniProt ID | K2C8_HUMAN | ||
| Gene Name | KRT8 | ||
| Gene ID | 3856 | ||
| Synonyms |
KRT8, CARD2, CK-8, CK8, CYK8, K2C8, K8, KO
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| Sequence |
MSIRVTQKSYKVSTSGPRAFSSRSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGASGM
GGITAVTVNQSLLSPLVLEVDPNIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKMLE TKWSLLQQQKTARSNMDNMFESYINNLRRQLETLGQEKLKLEAELGNMQGLVEDFKNKYE DEINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQLYEEEIRELQSQIS DTSVVLSMDNSRSLDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEELQSLAGKHGDDL RRTKTEISEMNRNISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKDANAKLSELEAAL QRAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESRLESGMQNMSIHTKTTSGYA GGLSSAYGGLTSPGLSYSLGSSFGSGAGSSSFSRTSSSRAVVVKKIETRDGKLVSESSDV LPK |
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| Pathway Map | MAP LINK | ||
| KEGG ID | hsa3856 | ||
| Pfam | PF00038; PF00261; PF04977; PF07888; PF07926; PF10473; PF11559; PF16208; PF16326; PF16331; PF19220 | ||
| Pair Name | Gamma-Tocotrienol, SU11274 | |||
| Phytochemical | Gamma-Tocotrienol | |||
| Drug | SU11274 | |||
| Disease Info | [ICD-11: 2C60] | Breast cancer | Investigative | |
| Regulate Info | Up-regulation | Keratin type II cytoskeletal 8 | Expression | |
| Result | Suggest that combined γ-tocotrienol and Met inhibitor treatment may provide benefit in treatment of breast cancers characterized by aberrant Met activity. | |||
