| Name | Keratin type I cytoskeletal 18 | ||
| UniProt ID | K1C18_HUMAN | ||
| Gene Name | KRT18 | ||
| Gene ID | 3875 | ||
| Synonyms |
KRT18, CK-18, CYK18, K18
|
||
| Sequence |
MSFTTRSTFSTNYRSLGSVQAPSYGARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGS
GGLATGIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKG PQVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVEN DIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAP KSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELR RTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQA QEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTTRRIVDGKVVS ETNDTKVLRH |
||
| Pathway Map | MAP LINK | ||
| KEGG ID | hsa3875 | ||
| Pfam | PF00038; PF07926 | ||
| Pair Name | Gamma-Tocotrienol, SU11274 | |||
| Phytochemical | Gamma-Tocotrienol | |||
| Drug | SU11274 | |||
| Disease Info | [ICD-11: 2C60] | Breast cancer | Investigative | |
| Regulate Info | Up-regulation | Keratin type I cytoskeletal 18 | Expression | |
| Result | Suggest that combined γ-tocotrienol and Met inhibitor treatment may provide benefit in treatment of breast cancers characterized by aberrant Met activity. | |||
