InterPAD - DETAILS

Germacrone, 6902-91-6, (3E,7E)-3,7-Dimethyl-10-(propan-2-ylidene)cyclodeca-3,7-dienone, Germacron, E2WQ6N4FBP, Germacrone (>90%), (3E,7E)-3,7-dimethyl-10-propan-2-ylidenecyclodeca-3,7-dien-1-one, (E,E)-Germacrone, Germacrone,(S), UNII-E2WQ6N4FBP, Germacrone, analytical standard, SCHEMBL2551615, SCHEMBL14215872, CHEBI:80830, CAULGCQHVOVVRN-SWZPTJTJSA-N, CAULGCQHVOVVRN-UPAULDTKSA-N, HY-N0440, MFCD00210050, s9311, AKOS016009673, CCG-266711, NCGC00482596-01, AC-34324, CS-0008961, G0519, (E,E)-Germacra-3,7(11),9-trien-6-one, C16966, Q-100776, Q15410959, trans,trans-3,7-dimethyl-10-isopropylidene-3,7-cyclodecadien-1-one, (3E,7E)-3,7-DIMETHYL-10-(1-METHYLETHYLIDENE)-3,7-CYCLODECADIEN-1-ONE

No.	Title	Href
1	Impact of fixed-dose combination of germacrone, curdione, and furanodiene on breast cancer cell proliferation. Cell J. 2013 Summer;15(2):160-5.	`Click`

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Title

Href

Impact of fixed-dose combination of germacrone, curdione, and furanodiene on breast cancer cell proliferation. Cell J. 2013 Summer;15(2):160-5.

Click

Name	Germacrone
PubChem CID	6436348
Molecular Weight	218.33g/mol
Synonyms	Germacrone, 6902-91-6, (3E,7E)-3,7-Dimethyl-10-(propan-2-ylidene)cyclodeca-3,7-dienone, Germacron, E2WQ6N4FBP, Germacrone (>90%), (3E,7E)-3,7-dimethyl-10-propan-2-ylidenecyclodeca-3,7-dien-1-one, (E,E)-Germacrone, Germacrone,(S), UNII-E2WQ6N4FBP, Germacrone, analytical standard, SCHEMBL2551615, SCHEMBL14215872, CHEBI:80830, CAULGCQHVOVVRN-SWZPTJTJSA-N, CAULGCQHVOVVRN-UPAULDTKSA-N, HY-N0440, MFCD00210050, s9311, AKOS016009673, CCG-266711, NCGC00482596-01, AC-34324, CS-0008961, G0519, (E,E)-Germacra-3,7(11),9-trien-6-one, C16966, Q-100776, Q15410959, trans,trans-3,7-dimethyl-10-isopropylidene-3,7-cyclodecadien-1-one, (3E,7E)-3,7-DIMETHYL-10-(1-METHYLETHYLIDENE)-3,7-CYCLODECADIEN-1-ONE
Drug Type	Small molecule
Formula	C₁₅H₂₂O
SMILES	CC1=CCC(=C(C)C)C(=O)CC(=CCC1)C
InChI	1S/C15H22O/c1-11(2)14-9-8-12(3)6-5-7-13(4)10-15(14)16/h7-8H,5-6,9-10H2,1-4H3/b12-8+,13-7+
InChIKey	CAULGCQHVOVVRN-SWZPTJTJSA-N
CAS Number	6902-91-6
ChEBI ID	CHEBI:80830
KEGG ID	C16966
Toxicity	Organism	Test Type	Route(Dose)
Structure			Download 2D MOL 3D MOL

Pair Name	Furanodiene, Germacrone
Partner Name	Furanodiene
Disease Info	[ICD-11: 2C60]	Breast cancer		Investigative
Biological Phenomena	Inhibition-->Cell proliferation
Gene Regulation	Up-regulation	Expression	BAX	hsa581
In Vitro Model	MDA-MB-231	Breast adenocarcinoma	Homo sapiens (Human)	CVCL_0062
In Vitro Model	MCF-7	Invasive breast carcinoma of no special type	Homo sapiens (Human)	CVCL_0031
Result	Unpredictable and complex interactions among different components in Curcuma WenyujinY.H.Chenet C Ling may exist. The intra-herb interactions should be taken into consideration when attempts are made to interpret the art of TCM formulation or other similar recipes.