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  1. General Info
  2. Effects Info
  3. Reference
Drug Interaction Details
01. General Information
Pair Name Gamma-Tocotrienol, Etoposide
Phytochemical Name Gamma-Tocotrienol (PubChem CID: 5282349 )
Anticancer drug Name Etoposide (PubChem CID: 36462 )
Structure of
Phytochemical
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Structure of
Anticancer Drug
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02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Enhancing Drug Efficacy
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Combination Pair ID: 593
Pair Name Gamma-Tocotrienol, Etoposide
Disease Info [ICD-11: 2C60] Breast cancer Investigative
Biological Phenomena Induction-->Apoptosis
In Vitro Model MCF-7 Invasive breast carcinoma of no special type Homo sapiens (Human) CVCL_0031
MDA-MB-231 Breast adenocarcinoma Homo sapiens (Human) CVCL_0062
Result Our results provide evidence for the profound anti-tumorigenic effect of combined etoposide and γ-tocotrienol in the breast cancer cell lines.
03. Reference
No. Title Href
1 Gamma-Tocotrienol Synergistically Promotes the Anti-proliferative and Pro-apoptotic Effects of Etoposide on Breast Cancer Cell Lines. Curr Mol Pharmacol. 2022;15(7):980-986. doi: 10.2174/1874467215666220131095611. Click
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