| Name | Glutathione peroxidase 1 | ||
| UniProt ID | GPX1_HUMAN | ||
| Gene Name | GPX1 | ||
| Gene ID | 2876 | ||
| Synonyms |
GPX1, GPXD, GSHPX1
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| Sequence |
MCAARLAAAAAAAQSVYAFSARPLAGGEPVSLGSLRGKVLLIENVASLUGTTVRDYTQMN
ELQRRLGPRGLVVLGFPCNQFGHQENAKNEEILNSLKYVRPGGGFEPNFMLFEKCEVNGA GAHPLFAFLREALPAPSDDATALMTDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYS RRFQTIDIEPDIEALLSQGPSCA |
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| Pathway Map | MAP LINK | ||
| KEGG ID | hsa2876 | ||
| TTD ID | T70654 | ||
| Pfam | PF00255; PF00578; PF08534 | ||
| Pair Name | Thymoquinone, Fluorouracil | |||
| Phytochemical | Thymoquinone | |||
| Drug | Fluorouracil | |||
| Disease Info | [ICD-11: 2A00-2F9Z] | Solid tumour or cancer | Investigative | |
| Regulate Info | Up-regulation | Glutathione peroxidase 1 | Expression | |
| Result | Our findings present the first report describing the in vivo enhancement effect of combined TQ and 5-FU against early stages of CRC; however, further studies are required to determine the value of this combination therapy in an advanced long-term model of CRC and also to realize its clinical potential. | |||
