| Name | Epithelial cell adhesion molecule | ||
| UniProt ID | EPCAM_HUMAN | ||
| Gene Name | EPCAM | ||
| Gene ID | 4072 | ||
| Synonyms |
EPCAM, Ber-Ep4, BerEp4, DIAR5, EGP-2, EGP314, EGP40, ESA, HNPCC8, KS1/4, KSA, LYNCH8, M4S1, MIC18, MK-1, MOC-31, TACSTD1, TROP1
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| Sequence |
MAPPQVLAFGLLLAAATATFAAAQEECVCENYKLAVNCFVNNNRQCQCTSVGAQNTVICS
KLAAKCLVMKAEMNGSKLGRRAKPEGALQNNDGLYDPDCDESGLFKAKQCNGTSMCWCVN TAGVRRTDKDTEITCSERVRTYWIIIELKHKAREKPYDSKSLRTALQKEITTRYQLDPKF ITSILYENNVITIDLVQNSSQKTQNDVDIADVAYYFEKDVKGESLFHSKKMDLTVNGEQL DLDPGQTLIYYVDEKAPEFSMQGLKAGVIAVIVVVVIAVVAGIVVLVISRKKRMAKYEKA EIKEMGEMHRELNA |
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| Pathway Map | MAP LINK | ||
| KEGG ID | hsa4072 | ||
| TTD ID | T47863 | ||
| Pfam | PF00086; PF01102; PF05454; PF06143; PF09534; PF12304; PF18635; PF21283 | ||
| Pair Name | Curcumin, Irinotecan | |||
| Phytochemical | Curcumin | |||
| Drug | Irinotecan | |||
| Disease Info | [ICD-11: 2B90] | Colon cancer | Investigative | |
| Regulate Info | Down-regulation | Epithelial cell adhesion molecule | Expression | |
| Result | The present data demonstrated that curcumin attenuated resistance to chemotherapeutic drugs through induction of apoptosis of CSCs among colon cancer cells. These findings may provide novel evidence for the therapeutic application of curcumin in CRC intervention. | |||
