| Name | Alpha-enolase | ||
| UniProt ID | ENOA_HUMAN | ||
| Gene Name | ENO1 | ||
| Gene ID | 2023 | ||
| Synonyms |
ENO1, ENO1-IT1, ENO1L1, HEL-S-17, MPB1, NNE, PPH
|
||
| Sequence |
MSILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGK
GVSKAVEHINKTIAPALVSKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCK AGAVEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFRE AMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYTDKV VIGMDVAASEFFRSGKYDLDFKSPDDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDD WGAWQKFTASAGIQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACKLA QANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSK AKFAGRNFRNPLAK |
||
| Pathway Map | MAP LINK | ||
| KEGG ID | hsa2023 | ||
| Pfam | PF00113; PF03952; PF07476; PF13378 | ||
| Pair Name | Cinnamaldehyde, Dacarbazine | |||
| Phytochemical | Cinnamaldehyde | |||
| Drug | Dacarbazine | |||
| Disease Info | [ICD-11: 2C30] | Melanoma | Investigative | |
| Regulate Info | Down-regulation | Alpha-enolase | Expression | |
| Result | As a covalent inhibitor of ENO1, CA combined with DTIC may be beneficial in patients with drug resistance in antimelanoma therapy. | |||
