| Pair Name | Cianidanol, Irinotecan | ||
| Phytochemical Name | Cianidanol (PubChem CID: 9064 ) | ||
| Anticancer drug Name | Irinotecan (PubChem CID: 60838 ) | ||
| Structure of Phytochemical |
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| Structure of Anticancer Drug |
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| Pair Name | Cianidanol, Irinotecan | |||
| Disease Info | [ICD-11: 2B90] | Colon cancer | Investigative | |
| In Vivo Model | It was investigated the antitumor effects of GT alone or in combination with IRN in inflammation-associated colon cancer mouse model induced by azoxymethane (AOM) and dextran sulfate sodium (DSS). | |||
| Result | GT significantly reduced the toxicity induced by IRN in terms of diarrhea, neutropenia, leucopenia, and NAFLD and works as an effective anticancer agent as it mitigates histopathology of colon adenocarcinoma. | |||
| No. | Title | Href |
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| 1 | Green tea catechins in combination with irinotecan attenuates tumorigenesis and treatment-associated toxicity in an inflammation-associated colon cancer mice model. J Egypt Natl Canc Inst. 2021 Jul 26;33(1):17. doi: 10.1186/s43046-021-00074-4. | Click |
