| Name | Interleukin-8 | ||
| UniProt ID | IL8_HUMAN | ||
| Gene Name | CXCL8 | ||
| Gene ID | 3576 | ||
| Synonyms |
CXCL8, GCP-1, GCP1, IL8, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1, SCYB8
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| Sequence |
MTSKLAVALLAAFLISAALCEGAVLPRSAKELRCQCIKTYSKPFHPKFIKELRVIESGPH
CANTEIIVKLSDGRELCLDPKENWVQRVVEKFLKRAENS |
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| Pathway Map | MAP LINK | ||
| KEGG ID | hsa3576 | ||
| TTD ID | T22658 | ||
| Pfam | PF00048; PF20902 | ||
| Pair Name | Tectochrysin, Cetuximab | |||
| Phytochemical | Tectochrysin | |||
| Drug | Cetuximab | |||
| Disease Info | [ICD-11: 2B90.Z] | Colon cancer | Investigative | |
| Regulate Info | Down-regulation | Interleukin-8 | Expression | |
| Result | Our results indicate that combined therapy with lower concentration of cetuximab and tectochrysin could significantly enhance the cancer cell growth inhibitory effect through the inhibition of EGFR signaling. | |||
