| Name | Crk-like protein | ||
| UniProt ID | CRKL_HUMAN | ||
| Gene Name | CRKL | ||
| Gene ID | 1399 | ||
| Synonyms |
CRKL
|
||
| Sequence |
MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSH
YIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPT AEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEK LVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFA KAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPD ENE |
||
| Pathway Map | MAP LINK | ||
| T.C. Number | 8.A.28.1.8 | ||
| KEGG ID | hsa1399 | ||
| Pfam | PF00017; PF00018; PF07653; PF14603; PF14604 | ||
| Pair Name | Forskolin, Ponatinib | |||
| Phytochemical | Forskolin | |||
| Drug | Ponatinib | |||
| Disease Info | [ICD-11: 2A20.1] | Chronic myelogenous leukemia | Investigative | |
| Regulate Info | Down-regulation | Crk-like protein | Phosphorylation | |
| Result | This study provides new insight into the biological underpinnings of BCR-ABL-driven CML and potential rationale for investigating novel treatment strategies for patients with T315I CML. | |||
