| Pair Name | Brusatol, Cisplatin | ||
| Phytochemical Name | Brusatol (PubChem CID: 73432 ) | ||
| Anticancer drug Name | Cisplatin (PubChem CID: 5702198 ) | ||
| Structure of Phytochemical |
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| Structure of Anticancer Drug |
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| Pair Name | Brusatol, Cisplatin | |||
| Disease Info | [ICD-11: 2B91.Z] | Colorectal cancer | Investigative | |
| Biological Phenomena | Induction-->Apoptosis | |||
| Gene Regulation | Up-regulation | Expression | BAX | hsa581 |
| In Vitro Model | CT26 | Mouse colon adenocarcinoma | Mus musculus (Mouse) | CVCL_7254 |
| Result | These results strongly suggested that the combination of CDDP and BR was able to produce a synergistic antitumor effect in CRC cells, thus providing a solid foundation for further development of this combination regimen into an effective therapeutic method for CRC. | |||
| No. | Title | Href |
|---|---|---|
| 1 | Synergistic antitumor effect of brusatol combined with cisplatin on colorectal cancer cells. Int J Mol Med. 2018 Mar;41(3):1447-1454. doi: 10.3892/ijmm.2018.3372. | Click |
