| Name | Ubiquitin-like-conjugating enzyme ATG3 | ||
| UniProt ID | ATG3_HUMAN | ||
| Gene Name | ATG3 | ||
| Gene ID | 64422 | ||
| Synonyms |
ATG3, APG3, APG3-LIKE, APG3L, PC3-96, hApg3
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| Sequence |
MQNVINTVKGKALEVAEYLTPVLKESKFKETGVITPEEFVAAGDHLVHHCPTWQWATGEE
LKVKAYLPTGKQFLVTKNVPCYKRCKQMEYSDELEAIIEEDDGDGGWVDTYHNTGITGIT EAVKEITLENKDNIRLQDCSALCEEEEDEDEGEAADMEEYEESGLLETDEATLDTRKIVE ACKAKTDAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRQPLTVEHMYEDISQDH VKKTVTIENHPHLPPPPMCSVHPCRHAEVMKKIIETVAEGGGELGVHMYLLIFLKFVQAV IPTIEYDYTRHFTM |
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| Pathway Map | MAP LINK | ||
| T.C. Number | 9.A.15.2.1 | ||
| KEGG ID | hsa64422 | ||
| Pfam | PF03987; PF11597 | ||
| Pair Name | Capsaicin, Fluorouracil | |||
| Phytochemical | Capsaicin | |||
| Drug | Fluorouracil | |||
| Disease Info | [ICD-11: 2C17] | Hepatocellular carcinoma | Investigative | |
| Regulate Info | Down-regulation | Ubiquitin-like-conjugating enzyme ATG3 | Expression | |
| Result | These results demonstrate that capsaicin may be a useful adjunct therapy to improve chemosensitivity in CCA. This effect likely occurs via PI3K/AKT/mTOR pathway activation, suggesting a promising strategy for the development of combination drugs for CCA. | |||
