| Name | 14-3-3 protein gamma | ||
| UniProt ID | 1433G_HUMAN | ||
| Gene Name | YWHAG | ||
| Gene ID | 7532 | ||
| Synonyms |
YWHAG, 14-3-3GAMMA, DEE56, EIEE56, PPP1R170
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| Sequence |
MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSW
RVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESK VFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYS VFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDD DGGEGNN |
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| Pathway Map | MAP LINK | ||
| T.C. Number | 8.A.98.1.11 | ||
| KEGG ID | hsa7532 | ||
| Pfam | PF00244; PF00901; PF12012; PF15499; PF16835 | ||
| Pair Name | Curcumenol, Cisplatin | |||
| Phytochemical | Curcumenol | |||
| Drug | Cisplatin | |||
| Disease Info | [ICD-11: 2C77] | Cervical cancer | Investigative | |
| Regulate Info | Down-regulation | 14-3-3 protein gamma | Expression | |
| Result | Curcumenol can enhance cisplatin to inhibit cancer cell proliferation, migration, and invasion and promote tumor cell apoptosis. The combination of drugs may promote the apoptosis of cervical cancer cells through the YWHAG pathway. | |||
