| Name | X-box-binding protein 1 | ||
| UniProt ID | XBP1_HUMAN | ||
| Gene Name | XBP1 | ||
| Gene ID | 7494 | ||
| Synonyms |
XBP1, TREB-5, TREB5, XBP-1, XBP2
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| Sequence |
MVVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARK
RQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLR EKTHGLVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAALRLRAPLQQVQAQL SPLQNISPWILAVLTLQIQSLISCWAFWTTWTQSCSSNALPQSLPAWRSSQRSTQKDPVP YQPPFLCQWGRHQPSWKPLMN |
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| Pathway Map | MAP LINK | ||
| KEGG ID | hsa7494 | ||
| Pfam | PF00170; PF03131; PF06156; PF07716; PF10303; PF14662 | ||
| Pair Name | Piperlongumine, Bortezomib | |||
| Phytochemical | Piperlongumine | |||
| Drug | Bortezomib | |||
| Disease Info | [ICD-11: 2C12] | Hepatocellular carcinoma | Investigative | |
| Regulate Info | Up-regulation | X-box-binding protein 1 | Expression | |
| Result | Piperlongumine and bortezomib synergically inhibit cholangiocarcinoma via ER stress-induced cell death | |||
| Pair Name | Honokiol, Paclitaxel | |||
| Phytochemical | Honokiol | |||
| Drug | Paclitaxel | |||
| Disease Info | [ICD-11: 2C25] | Lung cancer | Investigative | |
| Regulate Info | Up-regulation | X-box-binding protein 1 | Expression | |
| Result | Synergistic killing effect of paclitaxel and honokiol in non-small cell lung cancer cells through paraptosis induction | |||
| No. | Title | Href |
|---|---|---|
| 1 | Piperlongumine and bortezomib synergically inhibit cholangiocarcinoma via ER stress-induced cell death. Naunyn Schmiedebergs Arch Pharmacol. 2023 Jan;396(1):109-120. doi: 10.1007/s00210-022-02305-4. | Click |
| 2 | Synergistic killing effect of paclitaxel and honokiol in non-small cell lung cancer cells through paraptosis induction. Cell Oncol (Dordr). 2021 Feb;44(1):135-150. doi: 10.1007/s13402-020-00557-x. | Click |
