Name | Vascular endothelial growth factor B | ||
UniProt ID | VEGFB_HUMAN | ||
Gene Name | VEGFB | ||
Gene ID | 7423 | ||
Synonyms |
VEGFB, VEGFL, VRF
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Sequence |
MSPLLRRLLLAALLQLAPAQAPVSQPDAPGHQRKVVSWIDVYTRATCQPREVVVPLTVEL
MGTVAKQLVPSCVTVQRCGGCCPDDGLECVPTGQHQVRMQILMIRYPSSQLGEMSLEEHS QCECRPKKKDSAVKPDRAATPHHRPQPRSVPGWDSAPGAPSPADITHPTPAPGPSAHAAP STTSALTPGPAAAAADAAASSVAKGGA |
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Pathway Map | MAP LINK | ||
KEGG ID | hsa7423 | ||
TTD ID | T30040 | ||
Pfam | PF00341 |
Pair Name | Ginsenoside Rg3, Endostar | |||
Phytochemical | Ginsenoside Rg3 | |||
Drug | Endostar | |||
Disease Info | [ICD-11: 2C60] | Breast cancer | Investigative | |
Regulate Info | Down-regulation | Vascular endothelial growth factor B | Expression | |
Result | Endostar combined with ginsenoside Rg3 has stronger inhibiting effect on breast cancer tumor growth in tumor-bearing mice than single drug, and it can inhibit angiogenesis and cell invasion, and enhance cell autophagy. |