| Name | Voltage-dependent anion-selective channel protein 1 | ||
| UniProt ID | VDAC1_HUMAN | ||
| Gene Name | VDAC1 | ||
| Gene ID | 7416 | ||
| Synonyms |
VDAC1, PORIN, VDAC-1
|
||
| Sequence |
MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLET
KYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKR EHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQL HTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNS SLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA |
||
| Pathway Map | MAP LINK | ||
| T.C. Number | 1.A.1.20.1; 1.A.21.1.6; 1.A.9.1.7; 1.B.8.1.1; 1.B.8.1.12; 1.B.8.1.15 | ||
| KEGG ID | hsa7416 | ||
| TTD ID | T99397 | ||
| Pfam | PF01459 | ||
| Pair Name | Bisdemethoxycucurmin, Icotinib | |||
| Phytochemical | Bisdemethoxycucurmin | |||
| Drug | Icotinib | |||
| Disease Info | [ICD-11: 2C25.Z] | Lung cancer | Investigative | |
| Regulate Info | Up-regulation | Voltage-dependent anion-selective channel protein 1 | Expression | |
| Result | Our data indicate that BMDC has the potential to improve the treatment of primary EGFR-TKI resistant NISCLC that cannot be controlled with single-target agent, such as icotinib. | |||
