| Name | Dicarboxylate carrier SLC25A8 | ||
| UniProt ID | UCP2_HUMAN | ||
| Gene Name | UCP2 | ||
| Gene ID | 7351 | ||
| Synonyms |
UCP2, BMIQ4, SLC25A8, UCPH
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| Sequence |
MVGFKATDVPPTATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYR
GVMGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHASIGSRL LAGSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVNAYKTIAREEGFRGLWKGTS PNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKT RYMNSALGQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKRALMA ACTSREAPF |
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| Function |
//
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| Pathway Map | MAP LINK | ||
| T.C. Number | 2.A.29.3.4 | ||
| KEGG ID | hsa7351 | ||
| TTD ID | T84560 | ||
| Pair Name | Genipin, Everolimus | |||
| Phytochemical | Genipin | |||
| Drug | Everolimus | |||
| Disease Info | [ICD-11: 2C10.Z] | Pancreatic cancer | Investigative | |
| Regulate Info | Up-regulation | Dicarboxylate carrier SLC25A8 | Expression | |
| Result | These results reveal novel mechanisms through which UCP2 promotes cancer cell proliferation and support the combined inhibition of UCP2 and of Akt/mTOR pathway as a novel therapeutic strategy in the treatment of pancreatic adenocarcinoma. | |||
