| Name | Tyrosinase | ||
| UniProt ID | TYRO_HUMAN | ||
| Gene Name | TYR | ||
| Gene ID | 7299 | ||
| Synonyms |
TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3
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| Sequence |
MLLAVLYCLLWSFQTSAGHFPRACVSSKNLMEKECCPPWSGDRSPCGQLSGRGSCQNILL
SNAPLGPQFPFTGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFWGPNCTERRLLVR RNIFDLSAPEKDKFFAYLTLAKHTISSDYVIPIGTYGQMKNGSTPMFNDINIYDLFVWMH YYVSMDALLGGSEIWRDIDFAHEAPAFLPWHRLFLLRWEQEIQKLTGDENFTIPYWDWRD AEKCDICTDEYMGGQHPTNPNLLSPASFFSSWQIVCSRLEEYNSHQSLCNGTPEGPLRRN PGNHDKSRTPRLPSSADVEFCLSLTQYESGSMDKAANFSFRNTLEGFASPLTGIADASQS SMHNALHIYMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLQEVYPEANAPIGH NRESYMVPFIPLYRNGDFFISSKDLGYDYSYLQDSDPDSFQDYIKSYLEQASRIWSWLLG AAMVGAVLTALLAGLVSLLCRHKRKQLPEEKQPLLMEKEDYHSLYQSHL |
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| Pathway Map | MAP LINK | ||
| T.C. Number | 9.B.423.1.1 | ||
| KEGG ID | hsa7299 | ||
| TTD ID | T97035 | ||
| Pfam | PF00053; PF00264; PF06305; PF21094 | ||
| Pair Name | Aloin, Cisplatin | |||
| Phytochemical | Aloin | |||
| Drug | Cisplatin | |||
| Disease Info | [ICD-11: 2C30] | Melanoma | Investigative | |
| Regulate Info | Up-regulation | Tyrosinase | Expression | |
| Result | The results suggest that aloin possesses antineoplastic and antimetastatic properties, exerted likely through the induction of melanoma cell differentiation. | |||
