| Name | Tumor necrosis factor receptor superfamily member 10D | ||
| UniProt ID | TR10D_HUMAN | ||
| Gene Name | TNFRSF10D | ||
| Gene ID | 8793 | ||
| Synonyms |
TNFRSF10D, CD264, DCR2, TRAIL-R4, TRAILR4, TRUNDD
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| Sequence |
MGLWGQSVPTASSARAGRYPGARTASGTRPWLLDPKILKFVVFIVAVLLPVRVDSATIPR
QDEVPQQTVAPQQQRRSLKEEECPAGSHRSEYTGACNPCTEGVDYTIASNNLPSCLLCTV CKSGQTNKSSCTTTRDTVCQCEKGSFQDKNSPEMCRTCRTGCPRGMVKVSNCTPRSDIKC KNESAASSTGKTPAAEETVTTILGMLASPYHYLIIIVVLVIILAVVVVGFSCRKKFISYL KGICSGGGGGPERVHRVLFRRRSCPSRVPGAEDNARNETLSNRYLQPTQVSEQEIQGQEL AELTGVTVELPEEPQRLLEQAEAEGCQRRRLLVPVNDADSADISTLLDASATLEEGHAKE TIQDQLVGSEKLFYEEDEAGSATSCL |
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| Pathway Map | MAP LINK | ||
| KEGG ID | hsa8793 | ||
| Pfam | PF00020; PF05568; PF10717; PF15820 | ||
| Pair Name | Carnosic acid, Tamoxifen | |||
| Phytochemical | Carnosic acid | |||
| Drug | Tamoxifen | |||
| Disease Info | [ICD-11: 2C60] | Breast cancer | Investigative | |
| Regulate Info | Up-regulation | Tumor necrosis factor receptor superfamily member 10D | Expression | |
| Result | Our study supplies a novel therapeutic strategy to induce apoptosis for suppressing breast cancer, which was relied on Caspase-3/TRAIL activation. | |||
