Pair Name	Mangiferin, Cisplatin
Phytochemical Name	Mangiferin
Anticancer drug Name	Cisplatin
Disease Info	Nephrotoxicity			Investigative
Regulate Info	Up-regulation	Superoxide dismutase		Expression
Result	The study reveals a mechanistic basis of mangiferin action against cisplatin induced nephrotoxicity. Since Mangiferin shows synergistic anticancer activity with cisplatin, it can be considered as a promising drug candidate, to be used in combination with cisplatin.

Pair Name	Artesunate, TP-0903
Phytochemical	Artesunate
Drug	TP-0903
Disease Info	[ICD-11: 2C60]	Breast cancer		Investigative
Regulate Info	Down-regulation	Superoxide dismutase		Expression
Result	Synergistic interactions between TP-0903 and ART indicate that combination approaches involving these compounds can have therapeutic prospects for TNBC treatment.

Pair Name	Luteolin, SMC3
Phytochemical	Luteolin
Drug	SMC3
Disease Info	[ICD-11: 2C25]	Lung cancer		Investigative
Regulate Info	Down-regulation	Superoxide dismutase		Expression
Result	The results suggest that combination of SMC3 and luteolin is an effective approach for improving the anticancer value of SMC3, which has implications in cancer prevention and therapy.

Pair Name	Parthenolide, Doxorubicin
Phytochemical	Parthenolide
Drug	Doxorubicin
Disease Info	[ICD-11: 2C60]	Breast cancer		Investigative
Regulate Info	Down-regulation	Superoxide dismutase		Expression
Result	PN prevented the acquisition of resistance induced by Mitox and DOX treatment in MDA-MB231 cells. This effect was mediated by inhibition of overexpression of both Nrf2 and its target activities. Therefore, within MDA-MB231 cell lines, PN not only exerts toxic effects on stem-like cells, which are responsible for tumour recurrence, but also prevents drug resistance