| Name | Ras-related protein Rab-7a | ||
| UniProt ID | RAB7A_HUMAN | ||
| Gene Name | RAB7A | ||
| Gene ID | 7879 | ||
| Synonyms |
RAB7A, CMT2B, PRO2706, RAB7
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| Sequence |
MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQ
IWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPF VVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEV ELYNEFPEPIKLDKNDRAKASAESCSC |
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| Pathway Map | MAP LINK | ||
| T.C. Number | 9.A.3.1.1 | ||
| KEGG ID | hsa7879 | ||
| TTD ID | T14030 | ||
| Pfam | PF00006; PF00009; PF00025; PF00071; PF00503; PF00735; PF00931; PF01637; PF01926; PF02492; PF03029; PF03193; PF03266; PF04670; PF05729; PF07728; PF08477; PF09439; PF10662; PF12775; PF13173; PF13191; PF13401; PF13479; PF15423; PF20720 | ||
| Pair Name | Acteoside, Temozolomide | |||
| Phytochemical | Acteoside | |||
| Drug | Temozolomide | |||
| Disease Info | [ICD-11: 2A00] | Glioblastoma multiforme | Investigative | |
| Regulate Info | Up-regulation | Ras-related protein Rab-7a | Expression | |
| Result | It was also determined that TMZ + acteoside induced apoptosis and autophagy through the mitogen‑activated protein kinase signaling pathway. These findings suggest that acteoside has beneficial effects on TMZ‑based glioblastoma therapy. | |||
