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  1. General Info
  2. Effects Info
  3. Reference
Drug Interaction Details
01. General Information
Pair Name Quercetin, Cyclophosphamide
Phytochemical Name Quercetin (PubChem CID: 5280343 )
Anticancer drug Name Cyclophosphamide (PubChem CID: 2907 )
Structure of
Phytochemical
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Structure of
Anticancer Drug
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02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Combination Pair ID: 980
Pair Name Quercetin, Cyclophosphamide
Disease Info [ICD-11: 2C60] Breast cancer Investigative
Biological Phenomena Induction-->Immunomodulatory
In Vitro Model 4T1 Malignant neoplasms of the mouse mammary gland Mus musculus (Mouse) CVCL_0125
In Vivo Model 4T1 cells (5×10³) in 100 µL of phosphate-buffered saline (PBS) were injected into one axillary mammary fat pad per mouse of 5–6-week-old female immunocompetent BALB/c mice.
Result Complementarity between Microbiome and Immunity May Account for the Potentiating Effect of Quercetin on the Antitumor Action of Cyclophosphamide in a Triple-Negative Breast Cancer Model
03. Reference
No. Title Href
1 Complementarity between Microbiome and Immunity May Account for the Potentiating Effect of Quercetin on the Antitumor Action of Cyclophosphamide in a Triple-Negative Breast Cancer Model. Pharmaceuticals (Basel). 2023 Oct 6;16(10):1422. doi: 10.3390/ph16101422. Click
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