InterPAD - DETAILS

Pioglitazone, 111025-46-8, Actos, Glustin, Zactos, 105355-27-9, Pioglitazona, Pioglitazonum, 5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione, Pioglitazonum [INN-Latin], Pioglitazona [INN-Spanish], Piozone, Pioglu, AD-4833, U 72107, 5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione, Pioglitazone (Actos), CHEBI:8228, HSDB 7322, UNII-X4OV71U42S, 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione, pioglitazone (INN), X4OV71U42S, U-72107, Actos (TN), 105390-47-4, 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione, 2,4-thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-, DTXSID3037129, 5-(4-(2-(5-ethyl-2-pyridyl)ethoxy)benzyl)-2,4-thiazolidinedione, 5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]thiazolidine-2,4-dione, 5-[4-[2-(5-ETHYL-2-PYRIDYL)ETHOXY]BENZYL]-2,4-THIAZOLIDINEDIONE, 5-({4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione, MFCD00865504, PIOGLITAZONE [INN], 5-((4-(2-(5-Ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione, PIOGLITAZONE (IARC), PIOGLITAZONE [IARC], Pioglitazonum (INN-Latin), Pioglitazona (INN-Spanish), Pioglitazone [BAN:INN], Pioglitazone [INN:BAN], 5-(4-(2-(5-ETHYL-2-PYRIDYL)ETHOXY)BENZYL)THIAZOLIDINE-2,4-DIONE, (+/-)-5-(P-(2-(5-ETHYL-2-PYRIDYL)ETHOXY)BENZYL)-2,4-THIAZOLIDINEDIONE, 2,4-Thiazolidinedione, 5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-, 2,4-THIAZOLIDINEDIONE, 5-((4-(2-(5-ETHYL-2-PYRIDINYL)ETHOXY)PHENYL)METHYL)-, (+/-)-, C19H20N2O3S, U-72107E, Pioglitazone?, 5-{4-[2-(5-ethyl-2-pyridyl)ethoxy]benzyl}-2,4-thiazolidinedione, SR-01000763737, 5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)-1,3-thiazolidine-2,4-dione, 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-, (+/-)-, [( inverted exclamation markA)-5-[[4-[2-(5-ethyl-2-pyridinyl) ethoxy] phenyl] methyl]-2,4-] thiazolidinedione monohydrochlorid, Pioglitazone-[d4], Pioglitazone- Bio-X, HS-0047, Pioglitazonum (Latin), Spectrum_001623, Spectrum2_001679, Spectrum3_001002, Spectrum4_001130, Spectrum5_001480, Spectrum5_002067, PIOGLITAZONE [MI], PIOGLITAZONE [HSDB], SCHEMBL4121, PIOGLITAZONE [VANDF], BSPBio_002723, KBioGR_001619, KBioSS_002103, MLS006011848, PIOGLITAZONE [WHO-DD], SPBio_001897, GTPL2694, PIOGLITAZONE [EMA EPAR], DTXCID1017129, KBio2_002103, KBio2_004671, KBio2_007239, KBio3_001943, A10BG03, HYAFETHFCAUJAY-UHFFFAOYSA-N, HMS2089H14, HMS3651D09, HMS3712E16, HMS3884L10, Pharmakon1600-01504401, BCP26474, BBL029068, BDBM50103521, HB4139, NSC758876, s2590, STL309607, STL373406, (+/-)-5-[p-[2-(ethyl-2-pyridyl)ethoxy]benzyl]-2,4-thiazolidinedione, AKOS015894953, AKOS022109420, AC-1021, CCG-220107, CS-1700, DB01132, SB17323, (+/-)-5-[[4-[2-(5-Ethyl-2-pyridinyl)-ethoxy]phenyl]methyl]-2,4-thiazolidinedione, 2,4-Thiazolidinedione, 5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-, (+-)-, NCGC00163128-01, NCGC00163128-02, NCGC00163128-03, NCGC00163128-04, NCGC00163128-05, NCGC00163128-06, NCGC00163128-07, BP164273, HY-13956, SMR002204015, SY017473, SBI-0206791.P001, DB-027350, NS00000599, SW197561-3, C07675, D08378, EN300-117258, AB00698454-10, AB00698454_11, AB00698454_12, AB00698454_13, A802277, Q417765, J-002506, J-516181, SR-01000763737-5, BRD-A48430263-003-02-4, BRD-A48430263-003-06-5, Z1501480426, 5-[4-[2-(5-ethyl-2-pyridyl) ethoxy]benzyl]-2,4-thiazolidinedione, 5-[4-[2-(5-ethyl-2-pyridyl)eth-oxy]benzyl]-2,4-thiazolidinedione, 5-{4-[2-(5-ethyl-2-pyridyl)ethoxy]benzyl}-2,4thiazolidinedione, 5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)-thiazolidine-2,4-dione, 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl-2,4-thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridyl)ethoxy] phenyl]methyl]-2,4-thiazolidinedione, (+/-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione, (5S)-5-[[4-[2-(5-ethyl-2-pyridyl)ethoxy]phenyl]methyl]thiazolidine-2,4-dione;Pioglitazone, (RS)-5-(4-(2-(5-ETHYLPYRIDIN-2-YL)ETHOXY)BENZYL)THIAZOLIDINE-2,4-DIONE, 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]- (9CI), 5-[[4-[2-[(5-ethyl-2-pyridyl)]ethoxy]phenyl]methyl]thiazolidine- 2,4-dione, 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-4-hydroxy-1,3-thiazol-2(5H)-one, [()-5-[[4-[2-(5-ethyl-2-pyridinyl) ethoxy] phenyl] methyl]-2,4-] thiazolidinedione monohydrochlorid, 198077-89-3

Name	Pioglitazone
PubChem CID	4829
Molecular Weight	356.4g/mol
Synonyms	Pioglitazone, 111025-46-8, Actos, Glustin, Zactos, 105355-27-9, Pioglitazona, Pioglitazonum, 5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione, Pioglitazonum [INN-Latin], Pioglitazona [INN-Spanish], Piozone, Pioglu, AD-4833, U 72107, 5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione, Pioglitazone (Actos), CHEBI:8228, HSDB 7322, UNII-X4OV71U42S, 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione, pioglitazone (INN), X4OV71U42S, U-72107, Actos (TN), 105390-47-4, 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione, 2,4-thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-, DTXSID3037129, 5-(4-(2-(5-ethyl-2-pyridyl)ethoxy)benzyl)-2,4-thiazolidinedione, 5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]thiazolidine-2,4-dione, 5-[4-[2-(5-ETHYL-2-PYRIDYL)ETHOXY]BENZYL]-2,4-THIAZOLIDINEDIONE, 5-({4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione, MFCD00865504, PIOGLITAZONE [INN], 5-((4-(2-(5-Ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione, PIOGLITAZONE (IARC), PIOGLITAZONE [IARC], Pioglitazonum (INN-Latin), Pioglitazona (INN-Spanish), Pioglitazone [BAN:INN], Pioglitazone [INN:BAN], 5-(4-(2-(5-ETHYL-2-PYRIDYL)ETHOXY)BENZYL)THIAZOLIDINE-2,4-DIONE, (+/-)-5-(P-(2-(5-ETHYL-2-PYRIDYL)ETHOXY)BENZYL)-2,4-THIAZOLIDINEDIONE, 2,4-Thiazolidinedione, 5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-, 2,4-THIAZOLIDINEDIONE, 5-((4-(2-(5-ETHYL-2-PYRIDINYL)ETHOXY)PHENYL)METHYL)-, (+/-)-, C19H20N2O3S, U-72107E, Pioglitazone?, 5-{4-[2-(5-ethyl-2-pyridyl)ethoxy]benzyl}-2,4-thiazolidinedione, SR-01000763737, 5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)-1,3-thiazolidine-2,4-dione, 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-, (+/-)-, [( inverted exclamation markA)-5-[[4-[2-(5-ethyl-2-pyridinyl) ethoxy] phenyl] methyl]-2,4-] thiazolidinedione monohydrochlorid, Pioglitazone-[d4], Pioglitazone- Bio-X, HS-0047, Pioglitazonum (Latin), Spectrum_001623, Spectrum2_001679, Spectrum3_001002, Spectrum4_001130, Spectrum5_001480, Spectrum5_002067, PIOGLITAZONE [MI], PIOGLITAZONE [HSDB], SCHEMBL4121, PIOGLITAZONE [VANDF], BSPBio_002723, KBioGR_001619, KBioSS_002103, MLS006011848, PIOGLITAZONE [WHO-DD], SPBio_001897, GTPL2694, PIOGLITAZONE [EMA EPAR], DTXCID1017129, KBio2_002103, KBio2_004671, KBio2_007239, KBio3_001943, A10BG03, HYAFETHFCAUJAY-UHFFFAOYSA-N, HMS2089H14, HMS3651D09, HMS3712E16, HMS3884L10, Pharmakon1600-01504401, BCP26474, BBL029068, BDBM50103521, HB4139, NSC758876, s2590, STL309607, STL373406, (+/-)-5-[p-[2-(ethyl-2-pyridyl)ethoxy]benzyl]-2,4-thiazolidinedione, AKOS015894953, AKOS022109420, AC-1021, CCG-220107, CS-1700, DB01132, SB17323, (+/-)-5-[[4-[2-(5-Ethyl-2-pyridinyl)-ethoxy]phenyl]methyl]-2,4-thiazolidinedione, 2,4-Thiazolidinedione, 5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-, (+-)-, NCGC00163128-01, NCGC00163128-02, NCGC00163128-03, NCGC00163128-04, NCGC00163128-05, NCGC00163128-06, NCGC00163128-07, BP164273, HY-13956, SMR002204015, SY017473, SBI-0206791.P001, DB-027350, NS00000599, SW197561-3, C07675, D08378, EN300-117258, AB00698454-10, AB00698454_11, AB00698454_12, AB00698454_13, A802277, Q417765, J-002506, J-516181, SR-01000763737-5, BRD-A48430263-003-02-4, BRD-A48430263-003-06-5, Z1501480426, 5-[4-[2-(5-ethyl-2-pyridyl) ethoxy]benzyl]-2,4-thiazolidinedione, 5-[4-[2-(5-ethyl-2-pyridyl)eth-oxy]benzyl]-2,4-thiazolidinedione, 5-{4-[2-(5-ethyl-2-pyridyl)ethoxy]benzyl}-2,4thiazolidinedione, 5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)-thiazolidine-2,4-dione, 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl-2,4-thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridyl)ethoxy] phenyl]methyl]-2,4-thiazolidinedione, (+/-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione, (5S)-5-[[4-[2-(5-ethyl-2-pyridyl)ethoxy]phenyl]methyl]thiazolidine-2,4-dione;Pioglitazone, (RS)-5-(4-(2-(5-ETHYLPYRIDIN-2-YL)ETHOXY)BENZYL)THIAZOLIDINE-2,4-DIONE, 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]- (9CI), 5-[[4-[2-[(5-ethyl-2-pyridyl)]ethoxy]phenyl]methyl]thiazolidine- 2,4-dione, 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-4-hydroxy-1,3-thiazol-2(5H)-one, [()-5-[[4-[2-(5-ethyl-2-pyridinyl) ethoxy] phenyl] methyl]-2,4-] thiazolidinedione monohydrochlorid, 198077-89-3
Drug Type	Small molecule
Formula	C₁₉H₂₀N₂O₃S
SMILES	CCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3
InChI	1S/C19H20N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23)
InChIKey	HYAFETHFCAUJAY-UHFFFAOYSA-N
CAS Number	111025-46-8
ChEMBL ID	CHEMBL595
ChEBI ID	CHEBI:8228
TTD ID	D03OFF
Drug Bank ID	DB01132
KEGG ID	C07675
Toxicity	Organism	Test Type	Route(Dose)
	rat	LD50	intraperitoneal(165 mg/kg)
	mouse	LD50	intraperitoneal(254 mg/kg)
	rat	LD50	oral(322 mg/kg)
Structure			Download 2D MOL 3D MOL

Pair Name	Niacinamide, Pioglitazone
Partner Name	Niacinamide
Result	The efficacy of insulin and other antidiabetic agents may be diminished by certain drugs, including atypical antipsychotics, corticosteroids, diuretics, estrogens, gonadotropin-releasing hormone agonists, human growth hormone, phenothiazines, progestins, protease inhibitors, sympathomimetic amines, thyroid hormones, L-asparaginase, alpelisib, copanlisib, danazol, diazoxide, isoniazid, megestrol, omacetaxine, phenytoin, tagraxofusp, temsirolimus, as well as pharmacologic dosages of nicotinic acid and adrenocorticotropic agents. These drugs may interfere with blood glucose control because they can cause hyperglycemia, glucose intolerance, new-onset diabetes mellitus, and/or exacerbation of preexisting diabetes.