| Name | Securin | ||
| UniProt ID | PTTG1_HUMAN | ||
| Gene Name | PTTG1 | ||
| Gene ID | 9232 | ||
| Synonyms |
PTTG1, EAP1, ECRAR, HPTTG, PTTG, TUTR1
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| Sequence |
MATLIYVDKENGEPGTRVVAKDGLKLGSGPSIKALDGRSQVSTPRFGKTFDAPPALPKAT
RKALGTVNRATEKSVKTKGPLKQKQPSFSAKKMTEKTVKAKSSVPASDDAYPEIEKFFPF NPLDFESFDLPEEHQIAHLPLSGVPLMILDEERELEKLFQLGPPSPVKMPSPPWESNLLQ SPSSILSTLDVELPPVCCDIDI |
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| Pathway Map | MAP LINK | ||
| KEGG ID | hsa9232 | ||
| Pfam | PF04856 | ||
| Pair Name | Falcarindiol, Cisplatin | |||
| Phytochemical | Falcarindiol | |||
| Drug | Cisplatin | |||
| Disease Info | [ICD-11: 2C12] | Hepatocellular carcinoma | Investigative | |
| Regulate Info | Down-regulation | Securin | Expression | |
| Result | Our study illustrated that FAD is a potential anticancer drug and strengthens the chemosensitivity of HCC cells to DDP by inhibiting the STAT3/PTTG1 pathway. | |||
